HSPG2-Specific Polyklonaler Antikörper

HSPG2-Specific Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(3)

Kat-Nr. : 19675-1-AP

Synonyme

HSPG2, LG3 peptide, HSPG, heparan sulfate proteoglycan 2, Endorepellin

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  WB analysis of COLO 320 using 19675-1-AP

  COLO 320 cells were subjected to SDS PAGE followed by western blot with 19675-1-AP (HSPG2-Specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: COLO 320-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 2 publications below

Produktinformation

19675-1-AP bindet in WB, ELISA HSPG2-Specific und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: heparan sulfate proteoglycan 2
• Berechnetes Molekulargewicht: 469 kDa
• Beobachtetes Molekulargewicht: 469 kDa
• GenBank-Zugangsnummer: NM_005529
• Gene symbol: HSPG2
• Gene ID (NCBI): 3339
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HSPG2, also named as PLC and HSPG, is an integral component of basement membranes. It is responsible for the fixed negative electrostatic charge and is involved in the charge-selective ultrafiltration properties. It serves as an attachment substrate for cells. Defects in HSPG2 are the cause of Schwartz-Jampel syndrome (SJS1). Defects in HSPG2 are the cause of dyssegmental dysplasia Silverman-Handmaker type (DDSH). The antibody is specific to HSPG2.

Publikationen

Species	Application	Title
Human	WB	Int J Nanomedicine; Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway; Authors - Huimin Zhang
human	WB	Int J Biol Sci; Exosomal Transfer of Vasorin Expressed in Hepatocellular Carcinoma Cells Promotes Migration of Human Umbilical Vein Endothelial Cells.; Authors - Aixue Huang
		Nat Commun; An adeno-associated virus variant enabling efficient ocular-directed gene delivery across species; Authors - Shuang Luo