IL-4 Monoklonaler Antikörper
IL-4 Monoklonal Antikörper für FC (Intra)
Wirt / Isotyp
Ratte / IgG1
Getestete Reaktivität
Maus
Anwendung
FC (Intra)
Konjugation
CoraLite® Plus 647 Fluorescent Dye
CloneNo.
11B11
Kat-Nr. : CL647-65074
Synonyme
Galerie der Validierungsdaten
Geprüfte Anwendungen
Erfolgreiche Detektion in FC | PMA and ionomycin stimulated mouse Th2-polarized splenocytes |
Empfohlene Verdünnung
Anwendung | Verdünnung |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
CL647-65074 bindet in FC (Intra) IL-4 und zeigt Reaktivität mit Maus
Getestete Reaktivität | Maus |
Wirt / Isotyp | Ratte / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | Partially purified native mouse IL-4 |
Vollständiger Name | interleukin 4 |
GenBank-Zugangsnummer | BC027514 |
Gene symbol | Il4 |
Gene ID (NCBI) | 16189 |
Konjugation | CoraLite® Plus 647 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 654 nm / 674 nm |
Form | Liquid |
Reinigungsmethode | Affinitätsreinigung |
Lagerungspuffer | PBS mit 0,1% Natriumazid und 0,5% BSA, pH 7,3. |
Lagerungsbedingungen | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Interleukin-4 (IL-4), a member of the α-helical cytokine family, is produced by activated CD4+ T cells, basophils, and mast cells. It promotes the proliferation and differentiation of antigen presenting cells. IL-4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL-4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival. (PMID: 24489573;3049907;21663408)
Protokolle
Produktspezifische Protokolle | |
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FC protocol for CL Plus 647 IL-4 antibody CL647-65074 | Protokoll herunterladen |
Standard-Protokolle | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |