IL-4 Monoklonaler Antikörper

IL-4 Monoklonal Antikörper für FC (Intra)

Wirt / Isotyp

Ratte / IgG1

Getestete Reaktivität

Maus

Anwendung

FC (Intra)

Konjugation

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

11B11

Kat-Nr. : CL647-65074

Synonyme

Il 4, Il4, IL-4, interleukin 4



Geprüfte Anwendungen

Erfolgreiche Detektion in FCPMA and ionomycin stimulated mouse Th2-polarized splenocytes

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CL647-65074 bindet in FC (Intra) IL-4 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Ratte / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Partially purified native mouse IL-4
Vollständiger Name interleukin 4
GenBank-ZugangsnummerBC027514
Gene symbol Il4
Gene ID (NCBI) 16189
Konjugation CoraLite® Plus 647 Fluorescent Dye
Excitation/Emission maxima wavelengths654 nm / 674 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS mit 0,1% Natriumazid und 0,5% BSA, pH 7,3.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin-4 (IL-4), a member of the α-helical cytokine family, is produced by activated CD4+ T cells, basophils, and mast cells. It promotes the proliferation and differentiation of antigen presenting cells. IL-4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL-4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival. (PMID: 24489573;3049907;21663408)

Protokolle

Produktspezifische Protokolle
FC protocol for CL Plus 647 IL-4 antibody CL647-65074Protokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen