IL-1RL1/ST2 Monoklonaler Antikörper

IL-1RL1/ST2 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(18)

CloneNo.

7A2A7

Kat-Nr. : 60112-1-Ig

Synonyme

IL1RL1, 7A2A7, DER4, EC:3.2.2.6, FIT 1



Geprüfte Anwendungen

Erfolgreiche Detektion in WBHEK-293-Zellen, fetales humanes Hirngewebe, Maushirngewebe, PC-12-Zellen, Hausschwein-Hirngewebe, Rattenhirngewebe, Ratten-Cerebellum-Gewebe, ROS1728-Zellen, SGC-7901-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

KD/KOSee 1 publications below
WBSee 9 publications below

Produktinformation

60112-1-Ig bindet in WB, ELISA IL-1RL1/ST2 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman, Hausschwein, Maus
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen IL-1RL1/ST2 fusion protein Ag2555
Vollständiger Name interleukin 1 receptor-like 1
Berechnetes Molekulargewicht 63 kDa, 37 kDa, 30 kDa
Beobachtetes Molekulargewicht 63 kDa
GenBank-ZugangsnummerBC030975
Gene symbol IL1RL1
Gene ID (NCBI) 9173
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ST2, also known as IL1RL1, is a member of the IL-1 superfamily and serves as the receptor for IL-33. It plays a major role in immune and inflammatory responses. ST2 is expressed by various types of immune cells including Th2 cells, mast cells, type 2 innate lymphoid cells, eosinophils, basophils, NK cells, and non-immune cells, including cardiomyocytes. Two forms of ST2 exist: a membrane-bound form and a soluble form (sST2). The membrane-bound form activates the MyD88/NF-κB signaling pathway to enhance mast cell, Th2, regulatory T cell (Treg), and innate lymphoid cell type 2 functions. sST2 acts as a decoy receptor. (PMID: 27055914; 23999434; 28484466)

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for IL-1RL1/ST2 antibody 60112-1-IgProtokoll herunterladen
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
mouse

Immunity

Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis.

Authors - Zuojia Chen
mouse

Brain Behav Immun

Fibroblast-derived IL-33 exacerbates orofacial neuropathic pain via the activation of TRPA1 in trigeminal ganglion neurons

Authors - Yousuke Ikehata
human

Neurology

Association of Soluble ST2 With Functional Outcome, Perihematomal Edema, and Immune Response After Intraparenchymal Hemorrhage

Authors - Matthew B Bevers
humanWB

Sci Rep

Dysfunctional EAT thickness may promote maladaptive heart remodeling in CVD patients through the ST2-IL33 system, directly related to EPAC protein expression.

Authors - Elena Vianello
human

Sci Rep

Fatty acid-binding protein 5 limits ILC2-mediated allergic lung inflammation in a murine asthma model.

Authors - Shuhei Kobayashi
mouse

Cancer Biomark

Targeting IL-17alpha to promote anti-PD-1 therapy effect by screening the tumor immune microenvironment in a mouse oral carcinogenesis model

Authors - Shan Wang