Inhibin Beta A Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

Inhibin Beta A Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (1)

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(18)

Kat-Nr. : 10651-1-AP

Synonyme

INHBA, Inhibinβ-A, inhibin, beta A, Inhibin β-A, EDF

---

• 

---

Geprüfte Anwendungen

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 5 publications below
• IHC: See 12 publications below
• IF: See 3 publications below

Produktinformation

10651-1-AP bindet in WB, IHC, IF, ELISA Inhibin Beta A und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Inhibin Beta A fusion protein Ag1001
• Vollständiger Name: inhibin, beta A
• Berechnetes Molekulargewicht: 47 kDa
• Beobachtetes Molekulargewicht: 42 kDa
• GenBank-Zugangsnummer: BC007858
• Gene symbol: Inhibin beta A
• Gene ID (NCBI): 3624
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Inhibin is a 32-kD dimeric glycoprotein consisting of an alpha subunit and one of two beta subunits (beta A or beta B) leading to inhibin A or B, respectively, which was isolated and cloned on the basis of its ability to inhibit FSH release from the pituitary. Inhibin beta A forms a disulfide-linked homo-dimer known as activin A, which has been implicated in multiple biologic processes, including neoplastic progression. The inhibin beta A can also bind the beta B and A isoforms to form activin AB and inhibin, respectively.

Publikationen

Species	Application	Title
human	IF	Nat Commun; Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.; Authors - Yi-Ing Chen
		Development; Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination.; Authors - Dipankar J Dutta
	IHC	Cells; Single-Cell RNA-Seq Reveals Transcriptomic Heterogeneity and Post-Traumatic Osteoarthritis-Associated Early Molecular Changes in Mouse Articular Chondrocytes.; Authors - Aimy Sebastian
mouse	WB	PLoS One; Action mechanism of inhibin α-subunit on the development of Sertoli cells and first wave of spermatogenesis in mice.; Authors - Cai Kailai K
human	IHC,IF	Transl Oncol; Multiregion single cell analysis reveals a novel subtype of cancer-associated fibroblasts located in the hypoxic tumor microenvironment in colorectal cancer; Authors - Nanxin Zheng
		Hepatol Commun; Activin A is a prominent autocrine regulator of hepatocyte growth arrest.; Authors - Srividyameena Haridoss