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KLF5 Monoklonaler Antikörper
KLF5 Monoklonal Antikörper für WB, FC (Intra), ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human, Maus
Anwendung
WB, IHC, FC (Intra), ELISA
Konjugation
Unkonjugiert
CloneNo.
2C11C5
Kat-Nr. : 66850-1-Ig
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in WB | HeLa-Zellen, A549-Zellen, NCI-H1299-Zellen | 
| Erfolgreiche Detektion in FC (Intra) | HeLa-Zellen | 
Empfohlene Verdünnung
| Anwendung | Verdünnung | 
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 | 
| Durchflusszytometrie (FC) (INTRA) | FC (INTRA) : 0.50 ug per 10^6 cells in a 100 µl suspension | 
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Veröffentlichte Anwendungen
| KD/KO | See 1 publications below | 
| WB | See 4 publications below | 
| IHC | See 1 publications below | 
Produktinformation
66850-1-Ig bindet in WB, IHC, FC (Intra), ELISA KLF5 und zeigt Reaktivität mit human, Maus
| Getestete Reaktivität | human, Maus | 
| In Publikationen genannte Reaktivität | human | 
| Wirt / Isotyp | Maus / IgG1 | 
| Klonalität | Monoklonal | 
| Typ | Antikörper | 
| Immunogen | KLF5 fusion protein Ag15403 | 
| Vollständiger Name | Kruppel-like factor 5 (intestinal) | 
| Berechnetes Molekulargewicht | 457 aa, 51 kDa | 
| Beobachtetes Molekulargewicht | 51-57 kDa | 
| GenBank-Zugangsnummer | BC042131 | 
| Gene symbol | KLF5 | 
| Gene ID (NCBI) | 688 | 
| Konjugation | Unkonjugiert | 
| Form | Liquid | 
| Reinigungsmethode | Protein-G-Reinigung | 
| Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol | 
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. | 
Hintergrundinformationen
KLF5, also known as BTEB2 and IKLF, is a member of the Krueppel-like transcription factor family. It is a transcription factor for SMemb/non-muscle myosin heavy chain-B (NMHC-B). It is a molecular marker of phenotypically modulated smooth-muscle cells. KLF5 seems to be a key element linking external stress and cardiovascular remodeling.
Protokolle
| PRODUKTSPEZIFISCHE PROTOKOLLE | |
|---|---|
| WB protocol for KLF5 antibody 66850-1-Ig | Protokoll herunterladen | 
| FC protocol for KLF5 antibody 66850-1-Ig | Download protocol | 
| STANDARD-PROTOKOLLE | |
|---|---|
| Klicken Sie hier, um unsere Standardprotokolle anzuzeigen | 
Publikationen
| Species | Application | Title | 
|---|---|---|
| Adv Sci (Weinh) Positive Feedback Regulation between KLF5 and XPO1 Promotes Cell Cycle Progression of Basal like Breast Cancer
 | ||
| Int J Biol Sci Targeting the KLF5-EphA2 axis can restrain cancer stemness and overcome chemoresistance in basal-like breast cancer | ||
| Breast Cancer Res UCHL1 contributes to insensitivity to endocrine therapy in triple-negative breast cancer by deubiquitinating and stabilizing KLF5 | ||
| BMC Nephrol Depression of LncRNA DANCR alleviates tubular injury in diabetic nephropathy by regulating KLF5 through sponge miR-214-5p | ||
| Cancer Lett Energy Stress-activated AMPK Phosphorylates Snail1 and Suppresses its Stability and Oncogenic Function | 


