KLRG1 Monoklonaler Antikörper

KLRG1 Monoklonal Antikörper für FC

Wirt / Isotyp

Golden Syrian Hamster / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

2F1

Kat-Nr. : 65084-1-Ig

Synonyme

2F1 Ag, Klrg1, MAFA, MAFA L

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Galerie der Validierungsdaten

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  FC experiment of mouse splenocytes using 65084-1-Ig

  1X10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse KLRG1 (65084-1-Ig, Clone: 2F1) and FITC anti-Golden Syrian Hamster IgG Antibody at dilution 1:50 (green), or stained with 0.5 ug Golden Syrian Hamster IgG isotype control and FITC anti-Golden Syrian Hamster IgG Antibody at dilution 1:50 (black). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65084-1-Ig bindet in FC KLRG1 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Golden Syrian Hamster / IgG
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: killer cell lectin-like receptor subfamily G, member 1
• GenBank-Zugangsnummer: BC101953
• Gene symbol: Klrg1
• Gene ID (NCBI): 50928
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: Phosphatbasierter Puffer mit 0,09% Natriumazid, pH 7,2.
• Lagerungsbedingungen: Bei 2-8℃ lagern.

Hintergrundinformationen

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).