KLRG1 Monoklonaler Antikörper

KLRG1 Monoklonal Antikörper für FC

Wirt / Isotyp

Golden Syrian Hamster / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

CoraLite®594 Fluorescent Dye

CloneNo.

2F1

Kat-Nr. : CL594-65084

Synonyme

2F1 Ag, Klrg1, MAFA, MAFA L



Geprüfte Anwendungen

Erfolgreiche Detektion in FCMaus-Splenozyten

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CL594-65084 bindet in FC KLRG1 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Golden Syrian Hamster / IgG
Klonalität Monoklonal
Typ Antikörper
Immunogen k.A.
Vollständiger Name killer cell lectin-like receptor subfamily G, member 1
GenBank-ZugangsnummerBC101953
Gene symbol Klrg1
Gene ID (NCBI) 50928
Konjugation CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.09% sodium azide.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).

Protokolle

Produktspezifische Protokolle
FC protocol for CL594 KLRG1 antibody CL594-65084Protokoll herunterladen
Standard-Protokolle
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