LDOC1 Polyklonaler Antikörper

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• KD/KO Validated

LDOC1 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

Kat-Nr. : 10113-2-AP

Synonyme

LDOC1, Mar7, Mart7, Protein LDOC1

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• 

  WB analysis of HeLa using 10113-2-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 10113-2-AP (LDOC1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HeLa-Zellen, SKOV-3-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below

Produktinformation

10113-2-AP bindet in WB, ELISA LDOC1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LDOC1 fusion protein Ag0158
• Vollständiger Name: leucine zipper, down-regulated in cancer 1
• Berechnetes Molekulargewicht: 17 kDa
• Beobachtetes Molekulargewicht: 17 kDa, 25 kDa
• GenBank-Zugangsnummer: BC003104
• Gene symbol: LDOC1
• Gene ID (NCBI): 23641
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. LDOC1 localizes to the nucleus and is down-regulated in some cancer cell lines. LDOC1 regulates the transcriptional response mediated by the nuclear factor B (NF-kappa B). The gene encoding LDOC1 protein has been proposed as a tumor suppressor gene which may have an important role in the development and/or progression of some cancers.

Publikationen

Species	Application	Title
human	WB	Front Genet; Leucine zipper downregulated in cancer 1 may serve as a favorable prognostic biomarker by influencing proliferation, colony formation, cell cycle, apoptosis, and migration ability in hepatocellular carcinoma; Authors - Huaping Chen

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