LRRC52 Polyklonaler Antikörper

LRRC52 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25584-1-AP

Synonyme

LRRC52

---

• 

  WB analysis using 25584-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 25584-1-AP (LRRC52 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maus-Skelettmuskelgewebe, Ratten-Skelettmuskelgewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

25584-1-AP bindet in WB, ELISA LRRC52 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LRRC52 fusion protein Ag22354
• Vollständiger Name: leucine rich repeat containing 52
• Berechnetes Molekulargewicht: 313 aa, 35 kDa
• Beobachtetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: BC132981
• Gene symbol: LRRC52
• Gene ID (NCBI): 440699
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LRRC52 (leucine-rich repeat-containing protein 52) belongs to the gamma family of the BK channel accessory subunits, which potentially regulate the channel's gating properties (PMID: 22547800). It is dominantly expressed in testis and skeletal muscle, with much lower expression in several other tissues including placenta, kidney, lung, and some glands. LRRC52 has been reported as a Slo3 auxiliary subunit that helps define the specific alkalization dependence of KSper activation. LRRC52 has a calcular molecular weight of 35 kDa. This polyclonal antibody raised against 24-244aa of human LRRC52 reveals a band of 45 kDa, which is consistent with the molecular weight of glycosylated form of LRRC52 (PMID: 22084117).