LYSMD3 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

LYSMD3 Polyklonal Antikörper für WB, IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(3)

Kat-Nr. : 24313-1-AP

Synonyme

LysM and putative peptidoglycan-binding domain-containing protein 3

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  WB analysis of Neuro-2a using 24313-1-AP

  Neuro-2a cells were subjected to SDS PAGE followed by western blot with 24313-1-AP (LYSMD3 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

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  IHC staining of human liver using 24313-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 24313-1-AP (LYSMD3 Antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human liver using 24313-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 24313-1-AP (LYSMD3 Antibody) at dilution of 1:200 (under 40x lens).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Neuro-2a-Zellen
• Erfolgreiche Detektion in IHC: humanes Lebergewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:5000
• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 2 publications below

Produktinformation

24313-1-AP bindet in WB, IHC, ELISA LYSMD3 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LYSMD3 fusion protein Ag19430
• Vollständiger Name: LysM, putative peptidoglycan-binding, domain containing 3
• Berechnetes Molekulargewicht: 306 aa, 35 kDa
• Beobachtetes Molekulargewicht: 35 kDa
• GenBank-Zugangsnummer: BC136741
• Gene symbol: LYSMD3
• Gene ID (NCBI): 116068
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LYSMD3 also termed as LysM and putative peptidoglycan binding domain containing protein 3 is a 306 amino acid single-pass membrane protein that contains one LysM repeat. LysM domain encoding genes may play a role in brain and in nervous system development and functioning. LYSMD3, shows a high level of central nervous expression during embryogenesis and is also, therefore, a good candidate gene for other central nervous system (CNS) symptoms, such as psychomotor retardation, brain anomalies and muscular hypotonia of the 5q14.3 microdeletion syndrome.

Publikationen

Species	Application	Title
		J Biol Chem; LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens.; Authors - Christine C Yokoyama
human	WB	Mol Biol Cell; Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response.; Authors - Yevgeniy V Serebrenik
human	WB	Cell Rep; LYSMD3: A mammalian pattern recognition receptor for chitin.; Authors - Xin He ; KO Validated