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MTX1 Polyklonaler Antikörper
MTX1 Polyklonal Antikörper für WB, IP, ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human und mehr (2)
Anwendung
WB, IP, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 15529-1-AP
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in WB | HepG2-Zellen, A549-Zellen, HeLa-Zellen, Jurkat-Zellen |
Erfolgreiche IP | MCF-7-Zellen |
Empfohlene Verdünnung
Anwendung | Verdünnung |
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Western Blot (WB) | WB : 1:500-1:1000 |
Immunpräzipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Veröffentlichte Anwendungen
KD/KO | See 2 publications below |
WB | See 4 publications below |
IP | See 1 publications below |
Produktinformation
15529-1-AP bindet in WB, IP, ELISA MTX1 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
In Publikationen genannte Reaktivität | human, Maus, Ratte |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Polyklonal |
Typ | Antikörper |
Immunogen | MTX1 fusion protein Ag7685 |
Vollständiger Name | metaxin 1 |
Berechnetes Molekulargewicht | 51 kDa |
Beobachtetes Molekulargewicht | 35 kDa |
GenBank-Zugangsnummer | BC001906 |
Gene symbol | MTX1 |
Gene ID (NCBI) | 4580 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Antigen-Affinitätsreinigung |
Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
METAXINs are proteins located in the outer membrane of the mammalian mitochondrion. METAXIN 1 was characterized firstly and was found to play a role in the import of mitochondrial precursor proteins. It may also play a role in the assembly of b-barrel proteins into the outer membrane METAXIN1 was reported to be essential for survival of the postimplantation mouse embryo. METAXIN 1 has multiple transcripts. Several isoforms of METAXIN 1 exist due to the alternative splicing, with the predicted MW of 51, 48 and 36 kDa, respectively. Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane and form complex in the mitochondrion outer membrane.
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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WB protocol for MTX1 antibody 15529-1-AP | Protokoll herunterladen |
IP protocol for MTX1 antibody 15529-1-AP | Protokoll herunterladen |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
Species | Application | Title |
---|---|---|
Int J Biol Sci Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy.
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Hepatology Loss of Sam50 in hepatocytes induces cardiolipin-dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury | ||
J Cell Sci Myo19 tethers mitochondria to endoplasmic reticulum-associated actin to promote mitochondrial fission
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NPJ Parkinsons Dis Disruption of axonal transport in Parkinson's disease: the role of pathological α-Syn and AMPK/p38 MAPK signaling |