Malectin Polyklonaler Antikörper

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• KD/KO Validated

Malectin Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(8)

Kat-Nr. : 26655-1-AP

Synonyme

MLEC, KIAA0152

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  WB analysis using 26655-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 26655-1-AP (Malectin antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

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  WB analysis of human placenta using 26655-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 26655-1-AP (Malectin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of human placenta using 26655-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 26655-1-AP (Malectin antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maus-Kolongewebe, humanes Plazenta-Gewebe, Ratten-Kolongewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 7 publications below
• IF: See 2 publications below

Produktinformation

26655-1-AP bindet in WB, IF, ELISA Malectin und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Malectin fusion protein Ag24379
• Vollständiger Name: malectin
• Berechnetes Molekulargewicht: 292 aa, 32 kDa
• Beobachtetes Molekulargewicht: 32 kDa
• GenBank-Zugangsnummer: BC000371
• Gene symbol: Malectin
• Gene ID (NCBI): 9761
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Malectin is a conserved, endoplasmic reticulum (ER)-resident lectin that recognizes high mannose oligosaccharides displaying terminal glucose residues. Like other intracellular lectins involved in glycoprotein quality control, malectin is highly conserved in animals (PMID: 21298103).

Publikationen

Species	Application	Title
rat	WB	J Cell Biol; Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins; Authors - Amber M Cheatham
human	WB	Exp Cell Res; Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.; Authors - Ning Jiang ; KD Validated
		Mol Biol Cell; The prolyl isomerase FKBP11 is a secretory translocon accessory factor; Authors - Amanda DiGuilio
human	WB	Biochemistry; Integrated Structural Analysis of N-Glycans and Free Oligosaccharides Allows for a Quantitative Evaluation of ER Stress.; Authors - Naoki Fujitani
mouse	WB,IF	Nat Commun; The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes; Authors - Shuangcheng Alivia Wu
human	WB,IF	Int Immunopharmacol; Identification of TAP1 as a T-cell related therapeutic target in gastric cancer by mediating oxalipliatin-related synergistic enhancement of immunotherapy; Authors - Yupeng Zhao