NGFR/TNFRSF16 Rekombinanter Antikörper

NGFR/TNFRSF16 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242634B10

Kat-Nr. : 98391-2-RR

Synonyme

CD271, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor p75NGR

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  FC experiment of Transfected HEK-293T using 98391-2-RR

  1x10^6 HEK-293T cells or Ngfr transfected HEK-293T cells were stained with 0.25 ug Anti-Mouse NGFR/TNFRSF16 Rabbit RecAb (98391-2-RR, Clone:242634B10) and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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  FC experiment of Transfected HEK-293T using 98391-2-RR

  1x10^6 HEK-293T cells(left) or Ngfr transfected HEK-293T cells(right) were stained with 0.25 ug Anti-Mouse NGFR/TNFRSF16 Rabbit RecAb (98391-2-RR, Clone:242634B10) (red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Transfected HEK-293T cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98391-2-RR bindet in FC NGFR/TNFRSF16 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: nerve growth factor receptor (TNFR superfamily, member 16)
• Berechnetes Molekulargewicht: 46 kDa
• GenBank-Zugangsnummer: NM_033217.3
• Gene symbol: Ngfr
• Gene ID (NCBI): 18053
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

The nerve growth factor (NGF) receptor (NGFR), also known as p75NTR, TNFRSF16, belongs to the tumor necrosis factor receptor superfamily, which is a low-affinity receptor of neurotrophins including NGF,1 brain-derived neurotrophic factor (BDNF),2 and neurotrophin-3, -4, and -5.It is now apparent that expression of NGFR is ubiquitous and not limited to the nervous system, being expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells and myoepithelial cells (PMID: 38307025, 16424897).