- Featured Product
- KD/KO Validated
Neuropilin 1/CD304 Monoklonaler Antikörper
Neuropilin 1/CD304 Monoklonal Antikörper für WB, IF/ICC, ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
Hausschwein, human, Kaninchen und mehr (2)
Anwendung
WB, IF/ICC, IP, CoIP, ELISA
Konjugation
Unkonjugiert
CloneNo.
2H3F6
Kat-Nr. : 60067-1-Ig
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in WB | humanes Plazenta-Gewebe, A549-Zellen, fetales humanes Hirngewebe, HeLa-Zellen, MDA-MB-231-Zellen, Hausschwein-Hirngewebe, Hausschwein-Herzgewebe, Kaninchenherzgewebe |
Erfolgreiche Detektion in IF/ICC | SH-SY5Y-Zellen, humane embryonale Stammzellen |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
Western Blot (WB) | WB : 1:1000-1:6000 |
Immunfluoreszenz (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Veröffentlichte Anwendungen
KD/KO | See 3 publications below |
WB | See 15 publications below |
IF | See 10 publications below |
IP | See 2 publications below |
CoIP | See 1 publications below |
Produktinformation
60067-1-Ig bindet in WB, IF/ICC, IP, CoIP, ELISA Neuropilin 1/CD304 und zeigt Reaktivität mit Hausschwein, human, Kaninchen
Getestete Reaktivität | Hausschwein, human, Kaninchen |
In Publikationen genannte Reaktivität | human, Kaninchen, Maus, Krallenfrosch (Xenopus) |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | Neuropilin 1/CD304 fusion protein Ag0931 |
Vollständiger Name | neuropilin 1 |
Berechnetes Molekulargewicht | 103 kDa |
Beobachtetes Molekulargewicht | 130 kDa |
GenBank-Zugangsnummer | BC007737 |
Gene symbol | Neuropilin 1 |
Gene ID (NCBI) | 8829 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Neuropilin-1 (NRP1) is a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
---|---|
WB protocol for Neuropilin 1/CD304 antibody 60067-1-Ig | Protokoll herunterladen |
IF protocol for Neuropilin 1/CD304 antibody 60067-1-Ig | Protokoll herunterladen |
STANDARD-PROTOKOLLE | |
---|---|
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
Species | Application | Title |
---|---|---|
Elife Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons. | ||
Acta Biomater Semaphorin-3A, Neuropilin-1 and Plexin-A1 in Prosthetic-Particle Induced Bone Loss. | ||
J Pathol Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma. | ||
Am J Cancer Res CMTM6 promotes cell proliferation and invasion in oral squamous cell carcinoma by interacting with NRP1. | ||
Pharm Res Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy. | ||
Exp Eye Res Expression of axon guidance ligands and their receptors in the cornea and trigeminal ganglia and their recovery after corneal epithelium injury. |