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Neuropilin 1/CD304 Monoklonaler Antikörper
Neuropilin 1/CD304 Monoklonal Antikörper für WB, IF/ICC, ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
Hausschwein, human, Kaninchen und mehr (2)
Anwendung
WB, IF/ICC, IP, CoIP, ELISA
Konjugation
Unkonjugiert
CloneNo.
2H3F6
Kat-Nr. : 60067-1-Ig
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in WB | humanes Plazenta-Gewebe, A549-Zellen, fetales humanes Hirngewebe, HeLa-Zellen, MDA-MB-231-Zellen, Hausschwein-Hirngewebe, Hausschwein-Herzgewebe, Kaninchenherzgewebe |
| Erfolgreiche Detektion in IF/ICC | SH-SY5Y-Zellen, humane embryonale Stammzellen |
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Immunfluoreszenz (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Veröffentlichte Anwendungen
| KD/KO | See 3 publications below |
| WB | See 15 publications below |
| IF | See 10 publications below |
| IP | See 2 publications below |
| CoIP | See 1 publications below |
Produktinformation
60067-1-Ig bindet in WB, IF/ICC, IP, CoIP, ELISA Neuropilin 1/CD304 und zeigt Reaktivität mit Hausschwein, human, Kaninchen
| Getestete Reaktivität | Hausschwein, human, Kaninchen |
| In Publikationen genannte Reaktivität | human, Kaninchen, Maus, Krallenfrosch (Xenopus) |
| Wirt / Isotyp | Maus / IgG1 |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | Neuropilin 1/CD304 fusion protein Ag0931 |
| Vollständiger Name | neuropilin 1 |
| Berechnetes Molekulargewicht | 103 kDa |
| Beobachtetes Molekulargewicht | 130 kDa |
| GenBank-Zugangsnummer | BC007737 |
| Gene symbol | Neuropilin 1 |
| Gene ID (NCBI) | 8829 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-G-Reinigung |
| Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Neuropilin-1 (NRP1) is a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.
Protokolle
| PRODUKTSPEZIFISCHE PROTOKOLLE | |
|---|---|
| WB protocol for Neuropilin 1/CD304 antibody 60067-1-Ig | Protokoll herunterladen |
| IF protocol for Neuropilin 1/CD304 antibody 60067-1-Ig | Protokoll herunterladen |
| STANDARD-PROTOKOLLE | |
|---|---|
| Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
| Species | Application | Title |
|---|---|---|
Elife Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons. | ||
Acta Biomater Semaphorin-3A, Neuropilin-1 and Plexin-A1 in Prosthetic-Particle Induced Bone Loss. | ||
J Pathol Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma. | ||
Am J Cancer Res CMTM6 promotes cell proliferation and invasion in oral squamous cell carcinoma by interacting with NRP1. | ||
Pharm Res Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy. | ||
Exp Eye Res Expression of axon guidance ligands and their receptors in the cornea and trigeminal ganglia and their recovery after corneal epithelium injury. |










