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Neuropilin 1/CD304 Monoklonaler Antikörper

Neuropilin 1/CD304 Monoklonal Antikörper für WB, IF/ICC, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Kaninchen und mehr (2)

Anwendung

WB, IF/ICC, IP, CoIP, ELISA

Konjugation

Unkonjugiert

Publikationen(26)

CloneNo.

2H3F6

Kat-Nr. : 60067-1-Ig

Synonyme

Neuropilin 1, NRP1, 2H3F6, BDCA4, CD304



Geprüfte Anwendungen

Erfolgreiche Detektion in WBhumanes Plazenta-Gewebe, A549-Zellen, fetales humanes Hirngewebe, HeLa-Zellen, MDA-MB-231-Zellen, Hausschwein-Hirngewebe, Hausschwein-Herzgewebe, Kaninchenherzgewebe
Erfolgreiche Detektion in IF/ICCSH-SY5Y-Zellen, humane embryonale Stammzellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:1000-1:6000
Immunfluoreszenz (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

60067-1-Ig bindet in WB, IF/ICC, IP, CoIP, ELISA Neuropilin 1/CD304 und zeigt Reaktivität mit Hausschwein, human, Kaninchen

Getestete Reaktivität Hausschwein, human, Kaninchen
In Publikationen genannte Reaktivitäthuman, Kaninchen, Maus, Krallenfrosch (Xenopus)
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Neuropilin 1/CD304 fusion protein Ag0931
Vollständiger Name neuropilin 1
Berechnetes Molekulargewicht 103 kDa
Beobachtetes Molekulargewicht 130 kDa
GenBank-ZugangsnummerBC007737
Gene symbol Neuropilin 1
Gene ID (NCBI) 8829
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Neuropilin-1 (NRP1) is a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for Neuropilin 1/CD304 antibody 60067-1-IgProtokoll herunterladen
IF protocol for Neuropilin 1/CD304 antibody 60067-1-IgProtokoll herunterladen
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
XenopusIF

Elife

Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons.

Authors - Max Koppers
humanIF

Acta Biomater

Semaphorin-3A, Neuropilin-1 and Plexin-A1 in Prosthetic-Particle Induced Bone Loss.

Authors - S Saad
human

J Pathol

Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma.

Authors - Eric Morin
humanIF

Am J Cancer Res

CMTM6 promotes cell proliferation and invasion in oral squamous cell carcinoma by interacting with NRP1.

Authors - Yang Zheng
mouseWB

Pharm Res

Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy.

Authors - Yue Qiu
mouseIF

Exp Eye Res

Expression of axon guidance ligands and their receptors in the cornea and trigeminal ganglia and their recovery after corneal epithelium injury.

Authors - Victor H Guaiquil