EPCR/CD201 Polyklonaler Antikörper

EPCR/CD201 Polyklonal Antikörper für WB, IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

Kat-Nr. : 11391-1-AP

Synonyme

CD201, EPCR, PROCR, CCD41, CCCA

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  WB analysis of human spleen using 11391-1-AP

  human spleen tissue were subjected to SDS PAGE followed by western blot with 11391-1-AP (EPCR/CD201 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

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  IHC staining of human pancreas cancer using 11391-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 11391-1-AP (EPCR/CD201 antibody at dilution of 1:100 (under 10x lens).

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  IHC staining of human pancreas cancer using 11391-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 11391-1-AP (EPCR/CD201 antibody at dilution of 1:100 (under 40x lens).

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  IHC staining of human pancreas cancer using 11391-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 11391-1-AP (EPCR antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human lung cancer using 11391-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11391-1-AP (EPCR antibody at dilution of 1:100 (under 10x lens).

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  IHC staining of human lung cancer using 11391-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11391-1-AP (EPCR antibody at dilution of 1:100 (under 40x lens).

• 

  IHC staining of human lung cancer using 11391-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11391-1-AP (PROCR antibody at dilution of 1:100 (under 10x lens).

• 

  IHC staining of human lung cancer using 11391-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11391-1-AP (PROCR antibody at dilution of 1:100 (under 40x lens).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: humanes Milzgewebe
• Erfolgreiche Detektion in IHC: humanes Pankreaskarzinomgewebe, humanes Lungenkarzinomgewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000
• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

11391-1-AP bindet in WB, IHC, ELISA EPCR/CD201 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: EPCR/CD201 fusion protein Ag1937
• Vollständiger Name: protein C receptor, endothelial (EPCR)
• Berechnetes Molekulargewicht: 238 aa, 27 kDa
• Beobachtetes Molekulargewicht: 49 kDa
• GenBank-Zugangsnummer: BC014451
• Gene symbol: PROCR
• Gene ID (NCBI): 10544
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Protein C receptor (PROCR), also known as activated protein C receptor (APC receptor), EPCR, or CD201, is a transmembrane glycoprotein. EPCR promotes the activation of protein C, which has anticoagulant and cytoprotective effects. EPCR facilitates the activation of protein C by the thrombin-thrombomodulin complex but also facilitates APC-mediated cytoprotective effects on cells that involve the activation of protease-activated receptors (PAR) 1 and 3(PMID: 27207424).

Publikationen

Species	Application	Title
		Analyst; An iTRAQ based quantitative proteomic strategy to explore novel secreted proteins in metastatic hepatocellular carcinoma cell lines.; Authors - Yu Yanyan Y