TSLP Rekombinanter Antikörper

TSLP Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

241821B2

Kat-Nr. : 98247-1-RR

Synonyme

Thymic stromal lymphopoietin, 241821B2

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  FC experiment of HUVEC using 98247-1-RR

  1x10^6 untreated or IL-4, TNF-α and BFA-treated HUVEC cells were intracellularly stained with 0.25 ug Anti-Human TSLP Rabbit RecAb (98247-1-RR, Clone: 241821B2) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

• 

  Affinity and Kinetic Characterization of 98247-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98247-1-RR against Human TSLP were performed. The affinity constant is 2.85 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC (Intra): IL-4, TNF-α and BFA treated HUVEC cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98247-1-RR bindet in FC (Intra) TSLP und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: thymic stromal lymphopoietin
• Berechnetes Molekulargewicht: 18 kDa
• GenBank-Zugangsnummer: NM_033035.5
• Gene symbol: TSLP
• Gene ID (NCBI): 85480
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain, it mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. Another isoform of this protein may act as an antimicrobial peptide in the oral cavity and on the skin (PMID: 24850429).