- Featured Product
- KD/KO Validated
UQCRC1 Polyklonaler Antikörper
UQCRC1 Polyklonal Antikörper für WB, IHC, IF/ICC, IP, ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, IP, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 21705-1-AP
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in WB | HeLa-Zellen, humanes Hirngewebe, humanes Herzgewebe, humanes Skelettmuskelgewebe, Jurkat-Zellen, L02-Zellen, Mausnierengewebe, Maus-Dickdarmgewebe, Mauslebergewebe, Maus-Skelettmuskelgewebe, Mausmilzgewebe, Rattenlebergewebe |
| Erfolgreiche IP | HeLa-Zellen |
| Erfolgreiche Detektion in IHC | human normal colon, humanes Kolongewebe Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen. |
| Erfolgreiche Detektion in IF/ICC | HepG2-Zellen |
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| Immunpräzipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Immunhistochemie (IHC) | IHC : 1:100-1:1000 |
| Immunfluoreszenz (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Veröffentlichte Anwendungen
| KD/KO | See 3 publications below |
| WB | See 39 publications below |
| IHC | See 2 publications below |
| IF | See 3 publications below |
Produktinformation
21705-1-AP bindet in WB, IHC, IF/ICC, IP, ELISA UQCRC1 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| In Publikationen genannte Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | UQCRC1 fusion protein Ag16322 |
| Vollständiger Name | ubiquinol-cytochrome c reductase core protein I |
| Berechnetes Molekulargewicht | 480 aa, 53 kDa |
| Beobachtetes Molekulargewicht | 45 kDa |
| GenBank-Zugangsnummer | BC009586 |
| Gene symbol | UQCRC1 |
| Gene ID (NCBI) | 7384 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
UQCRC1(Cytochrome b-c1 complex subunit 1, mitochondrial), also named as QCR1 and UQCR1, is a ubunit of the cytochrome bc1 complex (complex III) of the mitochondrial respiratory chain, may mediate the formation of the complex between cytochromes c and c1. The gene encodes a 53 kDa protein with a 34 amino acids transit peptide. It is associated with apoptosis or inhibition of cancer cell growth.
Protokolle
| PRODUKTSPEZIFISCHE PROTOKOLLE | |
|---|---|
| WB protocol for UQCRC1 antibody 21705-1-AP | Protokoll herunterladen |
| IHC protocol for UQCRC1 antibody 21705-1-AP | Protokoll herunterladenl |
| IF protocol for UQCRC1 antibody 21705-1-AP | Protokoll herunterladen |
| IP protocol for UQCRC1 antibody 21705-1-AP | Protokoll herunterladen |
| STANDARD-PROTOKOLLE | |
|---|---|
| Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
| Species | Application | Title |
|---|---|---|
Sci Bull (Beijing) Targeted clearance of mitochondria by an autophagy-tethering compound (ATTEC) and its potential therapeutic effects | ||
Biomaterials Role of molybdenum in material immunomodulation and periodontal wound healing: Targeting immunometabolism and mitochondrial function for macrophage modulation. | ||
Theranostics Mitochondrial Protein UQCRC1 is Oncogenic and a Potential Therapeutic Target for Pancreatic Cancer. | ||
Acta Pharmacol Sin MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction. | ||
Int J Nanomedicine Activation of Dynamin-Related Protein 1 and Induction of Mitochondrial Apoptosis by Exosome-Rifampicin Nanoparticles Exerts Anti-Osteosarcoma Effect | ||
Aging (Albany NY) Celecoxib reverses the glioblastoma chemo-resistance to temozolomide through mitochondrial metabolism. |
Rezensionen
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH Xingyuan (Verified Customer) (06-30-2023) | Quality was alright, had non-specific band under it.
![]() |
FH Xingyuan (Verified Customer) (06-30-2023) | Quality was alright, had non-specific band under it.
|














