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  • KD/KO Validated

VLDLR Polyklonaler Antikörper

VLDLR Polyklonal Antikörper für WB, IF/ICC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (4)

Anwendung

WB, IF/ICC, ELISA

Konjugation

Unkonjugiert

Publikationen(10)

Kat-Nr. : 19493-1-AP

Synonyme

VLDL-R, VLDL receptor, Very low-density lipoprotein receptor



Geprüfte Anwendungen

Erfolgreiche Detektion in WBMCF-7-Zellen
Erfolgreiche Detektion in IF/ICCHeLa-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:500-1:1000
Immunfluoreszenz (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

19493-1-AP bindet in WB, IF/ICC, ELISA VLDLR und zeigt Reaktivität mit human

Getestete Reaktivität human
In Publikationen genannte Reaktivitäthuman, Huhn, Maus, Ratte, Zebrafisch
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name very low density lipoprotein receptor
Berechnetes Molekulargewicht 96 kDa
Beobachtetes Molekulargewicht 96 kDa
GenBank-ZugangsnummerNM_003383
Gene symbol VLDLR
Gene ID (NCBI) 7436
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

VLDLR binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. VLDLR binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (cytoplasmic domain of low-density lipoprotein receptor). For glycosylated, the MW of VLDLR migrates to ~160kd.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for VLDLR antibody 19493-1-APProtokoll herunterladen
IF protocol for VLDLR antibody 19493-1-APProtokoll herunterladen
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
zebrafishWB

Neuron

Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning.

Authors - Hilliard Austin T AT
mouseWB

Food Funct

Monounsaturated fatty acid-enriched olive oil exacerbates chronic alcohol-induced hepatic steatosis and liver injury in C57BL/6J mice

Authors - Rui Guo
ratWB

Front Pharmacol

Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats.

Authors - Xue Wu
mouseWB

PLoS One

Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.

Authors - Limin Liu
mouseWB

Front Nutr

Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol

Authors - Rui Guo
humanWB,IF

Front Oncol

VLDLR disturbs quiescence of breast cancer stem cells in a ligand-independent function

Authors - Mengying Yang
  • KD Validated

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

natalia (Verified Customer) (01-31-2025)

  • Applications: Immunohistochemistry, Immunofluorescence
  • Primary Antibody Dilution: 1:500
  • Cell Tissue Type: organoids