WDR1 Monoklonaler Antikörper

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• KD/KO Validated

WDR1 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

CloneNo.

2D11E1

Kat-Nr. : 67937-1-Ig

Synonyme

WD repeat containing protein 1, NORI-1, NORI 1, AIP1, Actin-interacting protein 1

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  WB analysis using 67937-1-Ig

  Various lysates were subjected to SDS PAGE followed by western blot with 67937-1-Ig (WDR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HEK-293 using 67937-1-Ig

  WB result of WDR1 antibody (67937-1-Ig; 1:10000; incubated at room temperature for 1.5 hours) with sh-Control and sh-WDR1 transfected HEK-293 cells.

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  WB analysis of rat testis using 67937-1-Ig

  rat testis tissue were subjected to SDS PAGE followed by western blot with 67937-1-Ig (WDR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: A549-Zellen, HEK-293-Zellen, Rattenhodengewebe, U-87-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below

Produktinformation

67937-1-Ig bindet in WB, ELISA WDR1 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: WDR1 fusion protein Ag30967
• Vollständiger Name: WD repeat domain 1
• Berechnetes Molekulargewicht: 606 aa, 66 kDa
• Beobachtetes Molekulargewicht: 65-66 kDa
• GenBank-Zugangsnummer: BC030541
• Gene symbol: WDR1
• Gene ID (NCBI): 9948
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

WDR1, which belongs to the WD repeat AIP1 family, also known as AIP1, is a 606 amino acid protein that localizes to the cytoskeleton. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WDR1 induces the disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PMID:15629458, 27557945, 29751004). WDR1 mutations may impair the ability of WDR1 to regulate cofilin-mediated actin depolymerization, and are associated with periodic fever, immunodeficiency, and thrombocytopenia syndrome (PMID: 27557945,27994071,29751004).

Publikationen

Species	Application	Title
human	WB	Acta Physiol (Oxf); The adipose-derived stem cell peptide ADSCP2 alleviates hypertrophic scar fibrosis via binding with pyruvate carboxylase and remodeling the metabolic landscape; Authors - Jingyun Li