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Anticorps Polyclonal de lapin anti-C4BPA

C4BPA Polyclonal Antibody for IHC, WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

N° de cat : 11819-1-AP

Synonymes

C4BP, C4BPA, Proline rich protein, PRP

Galerie de données de validation

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  • Western Blot (WB) analysis of human blood using C4BPA Polyclonal antibody (11819-1-AP)

    WB analysis of human blood using 11819-1-AP

    human blood were subjected to SDS PAGE followed by western blot with 11819-1-AP (C4BPA Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of human plasma using C4BPA Polyclonal antibody (11819-1-AP)

    WB analysis of human plasma using 11819-1-AP

    human plasma were subjected to SDS PAGE followed by western blot with 11819-1-AP (C4BPA Antibody) at dilution of 1:1000 incubated at 4 degree celsius over night.

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using C4BPA Polyclonal antibody (11819-1-AP)

    IHC staining of human liver cancer using 11819-1-AP

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 11819-1-AP (C4BPA Antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using C4BPA Polyclonal antibody (11819-1-AP)

    IHC staining of human liver cancer using 11819-1-AP

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 11819-1-AP (C4BPA Antibody) at dilution of 1:50 (under 40x lens).

Applications testées

Résultats positifs en WBtissu sanguin humain, tissu plasmatique humain
Résultats positifs en IHCtissu de cancer du foie humain
il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochimie (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

11819-1-AP cible C4BPA dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Réactivité citéeHumain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène C4BPA Protéine recombinante Ag2387
Nom complet complement component 4 binding protein, alpha
Masse moléculaire calculée 597 aa, 67 kDa
Poids moléculaire observé 70 kDa
Numéro d’acquisition GenBankBC022312
Symbole du gène C4BPA
Identification du gène (NCBI) 722
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

C4b-binding protein (C4BP) is a large oligomeric glycoprotein, present in plasma at a concentration of approximately 200 mg/L (PMID: 24218259). It is the main inhibitor of the classical complement and lectin pathway. C4BP is composed of two polypeptides (alpha and beta chains), which have molecular weights of 70 and 45 kDa, respectively (PMID: 7561113). This polyclonal antibody is raised against the C4BP alpha chain (C4BPA).

Protocole

Product Specific Protocols
WB protocol for C4BPA antibody 11819-1-APDownload protocol
IHC protocol for C4BPA antibody 11819-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle

Brain

Extracellular vesicle biomarkers for complement dysfunction in schizophrenia

Authors - Ting Xue
View Article
humanIHC

Oncotarget

Hepatitis B virus X protein up-regulates C4b-binding protein α through activating transcription factor Sp1 in protection of hepatoma cells from complement attack.

Authors - Guoxing Feng
View Article
humanWB

BMC Cancer

The imbalance in the complement system and its possible physiological mechanisms in patients with lung cancer.

Authors - Ping Zhao
View Article
humanWB

World J Surg Oncol

Proteomic analysis of small extracellular vesicles from the plasma of patients with hepatocellular carcinoma

Authors - Wei Dong
View Article