Anticorps Polyclonal de lapin anti-CCL18/MIP-4

CCL18/MIP-4 Polyclonal Antibody for IHC,ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, IF, ELISA

Conjugaison

Non conjugué

Publications

4

N° de cat : 22303-1-AP

Synonymes

AMAC 1, AMAC1, C C motif chemokine 18, CC chemokine PARC, CCL18, CKb7, DC CK1, DCCK1, Dendritic cell chemokine 1, MIP 4, MIP4, PARC, SCYA18, Small inducible cytokine A18

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Galerie de données de validation

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  IHC staining of human heart using 22303-1-AP

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 22303-1-AP (CCL18/MIP-4 antibody at dilution of 1:200 (under 10x lens).

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  IHC staining of human heart using 22303-1-AP

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 22303-1-AP (CCL18/MIP-4 antibody at dilution of 1:200 (under 40x lens).

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  IHC staining of human pancreas using 22303-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 22303-1-AP (CCL18/MIP-4 antibody at dilution of 1:50 (under 10x lens).

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  IHC staining of human pancreas using 22303-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 22303-1-AP (CCL18/MIP-4 antibody at dilution of 1:50 (under 40x lens).

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  IHC staining of human tonsillitis using 22303-1-AP

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22303-1-AP (CCL18/MIP-4 antibody at dilution of 1:50 (under 10x lens).

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  IHC staining of human tonsillitis using 22303-1-AP

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22303-1-AP (CCL18/MIP-4 antibody at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human heart using 22303-1-AP

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 22303-1-AP (CCL18/MIP-4 antibody at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human heart using 22303-1-AP

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 22303-1-AP (CCL18/MIP-4 antibody at dilution of 1:50 (under 40x lens).

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Applications testées

• Résultats positifs en IHC: tissu cardiaque humain, tissu d'amygdalite humain, tissu pancréatique humain; il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

• Immunohistochimie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• IHC: See 3 publications below
• IF: See 1 publications below

Informations sur le produit

22303-1-AP cible CCL18/MIP-4 dans les applications de IHC, IF, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
• Masse moléculaire calculée: 10 kDa
• Numéro d’acquisition GenBank: NM_002988
• Symbole du gène: CCL18
• Identification du gène (NCBI): 6362
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

CCL18 is a small cytokine belonging to the CC chemokine family. The effector functions that CCL18 exerts on the immune system is mainly on the adaptive immune system, while being produced and secreted mainly by innate immune system. Although the functions of CCL18 have been well studied in vitro, physiological effects of CCL18 in vivo have been difficult to characterize because there is no murine analog of CCL18. Only recently has the receptor for CCL18 been identified, and further characterization of CCL18 interactions with its receptor will lead to better understanding of the physiological role of CCL18 in humans.

Publications

Species	Application	Title
human	IHC	ACS Biomater Sci Eng; Matrisome Provides a Supportive Microenvironment for Skin Functions of Diverse Species.; Authors - Binghui Liu
human	IHC	Front Immunol; Novel macrophage-related gene prognostic index for glioblastoma associated with M2 macrophages and T cell dysfunction; Authors - Hang Ji
human	IHC	J Cell Physiol; Surgical trauma-induced CCL18 promotes recruitment of regulatory T cells and colon cancer progression.; Authors - Zhirong Sun
human	IF	Nat Commun; Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis; Authors - Shu Zhang