Anticorps Polyclonal de lapin anti-CCR2b-specific
CCR2b-specific Polyclonal Antibody for IHC, ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, souris
Applications
WB, IHC, IF, ELISA
Conjugaison
Non conjugué
N° de cat : 16154-1-AP
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en IHC | tissu de cancer du foie humain, tissu splénique de souris il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0. |
Dilution recommandée
| Application | Dilution |
|---|---|
| Immunohistochimie (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| WB | See 1 publications below |
| IHC | See 1 publications below |
| IF | See 2 publications below |
Informations sur le produit
16154-1-AP cible CCR2b-specific dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, souris
| Réactivité | Humain, souris |
| Réactivité citée | Humain |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | Peptide |
| Nom complet | chemokine (C-C motif) receptor 2 |
| Masse moléculaire calculée | 41 kDa |
| Numéro d’acquisition GenBank | NM_000648 |
| Symbole du gène | CCR2 |
| Identification du gène (NCBI) | 729230 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS with 0.02% sodium azide and 50% glycerol |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
CCR2 encodes a receptor for MCP1, functioning in inflammatory processes, tumor infiltration, and monocyte invasion of artery walls in atherosclerosis. There are two isoforms of CCR2, CCR2A and CCR2B. CCR2 isoforms were expressed by different cell subsets in both normal and IIM muscle. CCR2A was expressed in vessel walls and by some mononuclear cells, especially in cells involved in partial invasion in PM and IBM. CCR2B expression was observed in all satellite cells, in the muscular domain of neuromuscular junctions, and in some regenerative fibers of IIM, but not in inflammatory exudates. The sequences of the two isoforms are different from 314-374 aa. This antibody 16154-1-AP is raised against the peptide of 344-360 amino acids of CCR2b. It is specific to CCR2b.
Protocole
| Product Specific Protocols | |
|---|---|
| IHC protocol for CCR2b-specific antibody 16154-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Cell Rep Tissue-resident, extravascular Ly6c- monocytes are critical for inflammation in the synovium | ||
Int J Mol Sci Inducing Receptor Degradation as a Novel Approach to Target CC Chemokine Receptor 2 (CCR2) | ||
Cancer Med Combination therapy with bevacizumab and a CCR2 inhibitor for human ovarian cancer: An in vivo validation study |
Avis
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH Larissa (Verified Customer) (04-14-2025) | We've used the CCR2b-specific Rabbit Polyclonal Antibody for both Western blot and immunohistochemistry with great results. Overall, a reliable and high-quality antibody that performs well in multiple applications.
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