Anticorps Monoclonal anti-CD103

CD103 Monoclonal Antibody for FC

Hôte / Isotype

Hamster / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

2E7

N° de cat : CL647-65047

Synonymes

A530055J10, alpha E1, alpha M290, aM290, CD103, Integrin alpha E, Itgae



Applications testées

Résultats positifs en cytométriesplénocytes de souris

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-65047 cible CD103 dans les applications de FC et montre une réactivité avec des échantillons souris

Réactivité souris
Hôte / Isotype Hamster / IgG
Clonalité Monoclonal
Type Anticorps
Immunogène Lymphocytes intraépithéliaux (LIE) intestinaux de souris C57BL/6J
Nom complet integrin alpha E, epithelial-associated
Numéro d’acquisition GenBankBC150690
Symbole du gène CD103
Identification du gène (NCBI) 16407
Conjugaison CoraLite® Plus 647 Fluorescent Dye
Excitation/Emission maxima wavelengths654 nm / 674 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide and 0.5% BSA
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD103, also known as integrin alpha-E (ITGAE) or integrin alpha-IEL, is a type I transmembrane integrin protein that binds integrin beta 7 to form Integrin alpha-E beta-7 which is a receptor for E-cadherin and mediates adhesion of T lymphocytes to epithelial cells (PMID: 7969453; 8468482). CD103 is expressed on intraepithelial lymphocyte (IEL) T cells (both alpha/beta T cells and gamma/delta T cells), some peripheral regulatory T cells (Tregs), lamina propria T cells, and a subset of dendritic cells in the gut mucosa and mesenteric lymph nodes (PMID: 12242333; 15608520; 16216890).

Protocole

Product Specific Protocols
FC protocol for CL Plus 647 CD103 antibody CL647-65047Download protocol
Standard Protocols
Click here to view our Standard Protocols
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