Anticorps Monoclonal anti-CD106

CD106 Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

1.G11B1

N° de cat : 65049-1-Ig

Synonymes

CD106, DKFZp779G2333, INCAM 100, V CAM 1, VCAM 1, VCAM1

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Galerie de données de validation

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  FC experiment of HUVEC using 65049-1-Ig

  1X10^6 TNF-alpha treated HUVEC cells were surface stained with 0.25 ug Anti-Human CD106 (65049-1-Ig, Clone: 1.G11B1) and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (green), or stained with 0.25 ug mouse IgG1 isotype control and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (black). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules HUVEC,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65049-1-Ig cible CD106 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: s/o
• Nom complet: vascular cell adhesion molecule 1
• Masse moléculaire calculée: 739 aa, 81 kDa
• Numéro d’acquisition GenBank: BC017276
• Symbole du gène: VCAM1
• Identification du gène (NCBI): 7412
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: Solution saline tamponnée au borate, pH 8,2.
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843).