Anticorps Recombinant de lapin anti-CD79a

CD79a Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC (Intra)

Conjugaison

APC Fluorescent Dye

CloneNo.

241299F3

N° de cat : APC-FcA98072

Synonymes

MB-1 membrane glycoprotein, MB1, MB 1 membrane glycoprotein, MB 1, B-cell antigen receptor complex-associated protein alpha chain

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Galerie de données de validation

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  FC experiment of human PBMCs using APC-FcA98072

  1x10^6 human PBMCs were intracellularly stained with FcZero-rAb™ PE Anti-Human CD19 (4G7) and 5 ul APC Anti-Human CD79a Rabbit RecAb (APC-FcA98072, Clone:241299F3) or APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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Applications testées

• Résultats positifs en FC (Intra): CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

APC-FcA98072 cible CD79a dans les applications de FC (Intra) et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD79a molecule, immunoglobulin-associated alpha
• Masse moléculaire calculée: 226 aa, 25 kDa
• Numéro d’acquisition GenBank: BC113733
• Symbole du gène: CD79A
• Identification du gène (NCBI): 973
• Conjugaison: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD79a, also named as B-cell antigen receptor complex-associated protein alpha chain or MB-1 membrane glycoprotein, is a 226 amino acid protein, which contains one ITAM domain and one Ig-like C2-type (immunoglobulin-like) domain. CD79A is expressed in B cells and localizes in the cell membrane. CD79A is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79A is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.

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