Anticorps Polyclonal de lapin anti-hCG Beta

• Phare
• Validé par KD/KO

hCG Beta Polyclonal Antibody for IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(15)

N° de cat : 11615-1-AP

Synonymes

CGB, CGB,hCG, CG beta, CGB3, CGbeta

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Galerie de données de validation

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  IHC staining of human placenta using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 10x lens).

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  IHC staining of human placenta using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 40x lens).

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  IHC staining of human placenta using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human placenta using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 40x lens).

• 

  IHC staining of human breast cancer using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human breast cancer using 11615-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11615-1-AP (hCG beta antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Applications testées

• Résultats positifs en IHC: tissu placentaire humain, tissu de cancer du sein humain; il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

• Immunohistochimie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 11 publications below
• IHC: See 2 publications below
• IF: See 4 publications below

Informations sur le produit

11615-1-AP cible hCG Beta dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: hCG Beta Protéine recombinante Ag2191
• Nom complet: CG beta
• Masse moléculaire calculée: 165 aa, 18 kDa
• Numéro d’acquisition GenBank: BC022796
• Symbole du gène: hCG Beta
• Identification du gène (NCBI): 1082
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Beta-hCG (beta-human chorionic gonadotropin) is a glycoprotein hormone produced by the placenta during pregnancy. It is a critical marker used in both obstetrics and oncology for various diagnostic and monitoring purposes. hCG is composed of two subunits: an alpha subunit (similar to other glycoprotein hormones like LH, FSH, and TSH) and a unique beta subunit (β-hCG). The beta subunit is the primary focus for diagnostic tests due to its specificity. β-hCG is initially secreted by the syncytiotrophoblast cells surrounding the developing embryo and later by the placenta.

Publications

Species	Application	Title
human	WB	J Transl Med; STK40 inhibits trophoblast fusion by mediating COP1 ubiquitination to degrade P57Kip2; Authors - Xia Li
human	WB,IHC	iScience; Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus; Authors - Jie Ning
human	IF	EBioMedicine; Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta.; Authors - Fangfang Wang
human	IF	Cell Signal; Hypermethylation and low expression of FOXM1 predisposes women to unexplained recurrent miscarriage by impairing trophoblast stem cell proliferation; Authors - Youqing Jiang
human	WB	Mol Cell Endocrinol; Activation of G protein-coupled estrogen receptor stimulates placental human chorionic gonadotropin expression through PKA-CREB signaling; Authors - Sizhu Yang
human	WB	Biomolecules; Calnexin Is Involved in Forskolin-Induced Syncytialization in Cytotrophoblast Model BeWo Cells; Authors - Hitomi Matsukawa

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