Anticorps Polyclonal de lapin anti-Claudin 7

Claudin 7 Polyclonal Antibody for IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF, ELISA

Conjugaison

Non conjugué

Publications

10

N° de cat : 10118-1-AP

Synonymes

CEPTRL2, Claudin 7, CLDN 7, CLDN7, CPETRL2, Hs.84359

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Galerie de données de validation

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  IHC staining of human breast cancer using 10118-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10118-1-AP (Claudin 7 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human breast cancer using 10118-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10118-1-AP (Claudin 7 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human breast cancer using 10118-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10118-1-AP (Claudin 7 antibody at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human breast cancer using 10118-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10118-1-AP (Claudin 7 antibody at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Applications testées

• Résultats positifs en IHC: tissu de cancer du sein humain; il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

• Immunohistochimie (IHC): IHC : 1:200-1:800

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• IHC: See 1 publications below
• IF: See 5 publications below

Informations sur le produit

10118-1-AP cible Claudin 7 dans les applications de IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Claudin 7 Protéine recombinante Ag0159
• Nom complet: claudin 7
• Masse moléculaire calculée: 22.4 kDa
• Poids moléculaire observé: 23 kDa
• Numéro d’acquisition GenBank: BC001055
• Symbole du gène: CLDN7
• Identification du gène (NCBI): 1366
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Claudins are a family of proteins that are the most important components of tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. They are small (20-27 kilodalton (kDa)) proteins with very similar structures. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm.

Publications

Species	Application	Title
human		Cancers (Basel); Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin-Low Triple Negative Breast Cancer Cells.; Authors - Fayola Levine
mouse	IF	iScience; Commercial dishes with gelatin-free microstructured inserts for elongated stem cell self-renewal and pluripotency; Authors - Qian Ban
mouse		Stem Cell Res Ther; Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis.; Authors - Ya Yang
mouse	IF	FASEB J; Steroid receptor coactivator-2 drives epithelial reprogramming that enables murine embryo implantation; Authors - Vineet K Maurya
mouse		Front Pharmacol; Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase.; Authors - Bei Yue
mouse	IF	Biol Reprod; Pre-implantation triclosan exposure alters uterine receptivity through affecting tight junction protein†.; Authors - Guangzhu Dong

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