Anticorps Polyclonal de lapin anti-Cathepsin G

Cathepsin G Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications

3

N° de cat : 23840-1-AP

Synonymes

Cathepsin G, CG, CTSG

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Galerie de données de validation

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  WB analysis of MCF-7 using 23840-1-AP

  MCF-7 cells were subjected to SDS PAGE followed by western blot with 23840-1-AP (Cathepsin G antibody at dilution of 1:600 incubated at room temperature for 1.5 hours.

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  WB analysis of MDA-MB-453s using 23840-1-AP

  MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with 23840-1-AP (Cathepsin G antibody at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules MCF-7, cellules MDA-MB-453s

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below

Informations sur le produit

23840-1-AP cible Cathepsin G dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Cathepsin G Protéine recombinante Ag20818
• Nom complet: cathepsin G
• Masse moléculaire calculée: 29 kDa
• Poids moléculaire observé: 29 kDa, 35 kDa
• Numéro d’acquisition GenBank: BC014460
• Symbole du gène: CTSG
• Identification du gène (NCBI): 1511
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

CTSG(Cathepsin G) is also named as CTLA, CG, MGC23078, Catg and belongs to the peptidase S1 family. It may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. CTSG may also play a role in the progression to heart failure by activating angiotensin II, leading to detrimental effects on the heart. The full length protein contains 255 amino acid and has a signal peptide, a propeptide and a glycosylation site.

Publications

Species	Application	Title
human	WB	Cancer Cell; Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation.; Authors - Yansen Xiao
human	WB	Front Immunol; A Novel Immune-Related Gene Signature to Identify the Tumor Microenvironment and Prognose Disease Among Patients With Oral Squamous Cell Carcinoma Patients Using ssGSEA: A Bioinformatics and Biological Validation Study; Authors - Yun Chen
		PLoS One; Stable depletion of RUNX1-ETO in Kasumi-1 cells induces expression and enhanced proteolytic activity of Cathepsin G and Neutrophil Elastase.; Authors - Caroline Schoenherr