• Phare
  • Validé par KD/KO

Anticorps Polyclonal de lapin anti-CXCL10/IP-10

CXCL10/IP-10 Polyclonal Antibody for WB, IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain et plus (2)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(53)

N° de cat : 10937-1-AP

Synonymes

CXCL10, CXCL10/IP10, IP10, 10 kDa interferon gamma-induced protein, C X C motif chemokine 10



Applications testées

Résultats positifs en WBIFN gamma, LPS and Brefeldin A treated THP-1 cells,
Résultats positifs en IHCtissu de cirrhose hépatique humain, tissu de cancer du foie humain, tissu de carcinome nasopharyngé humain, tissu de tumeur ovarienne humain
il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochimie (IHC)IHC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

10937-1-AP cible CXCL10/IP-10 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Réactivité citéerat, Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CXCL10/IP-10 Protéine recombinante Ag1369
Nom complet chemokine (C-X-C motif) ligand 10
Masse moléculaire calculée 11 kDa
Poids moléculaire observé11 kDa
Numéro d’acquisition GenBankBC010954
Symbole du gène CXCL10
Identification du gène (NCBI) 3627
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS with 0.02% sodium azide and 50% glycerol
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

CXCL10 (also known as IP-10) is a member of the CXC chemokine family which binds to the CXCR3 receptor to exert its biological effects. CXCL10 is a 12-kDa protein and constitutes two internal disulfide cross bridges. The predicted signal peptidase cleavage generates a 10-kDa secreted polypeptide with four conserved cysteine residues in the N-terminal. The CXCL10 gene localizes on chromosome 4 at band q21, a locus associated with an acute monocytic/B-lymphocyte lineage leukemia exhibiting translocation of t (4; 11) (q21; q23). CXCL10 mediates leukocyte trafficking, adaptive immunity, inflammation, haematopoiesis and angiogenesis. Under proinflammatory conditions CXCL10 is secreted from a variety of cells, such as leukocytes, activated neutrophils, eosinophils, monocytes, epithelial cells, endothelial cells, stromal cells (fibroblasts) and keratinocytes in response to IFN-γ.

Protocole

Product Specific Protocols
WB protocol for CXCL10/IP-10 antibody 10937-1-APDownload protocol
IHC protocol for CXCL10/IP-10 antibody 10937-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Cancer Lett

PARP inhibitor plus radiotherapy reshape the immune suppressive microenvironment and potentiate the efficacy of immune checkpoint inhibitors in tumors with IDH1 mutation

Authors - Xiaoyu Hu
humanIHC

J Mater Chem B

Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating

Authors - Bin Yan
mouse,humanIHC

Front Immunol

LRPPRC facilitates tumor progression and immune evasion through upregulation of m6A modification of PD-L1 mRNA in hepatocellular carcinoma

Authors - Houhong Wang
humanIHC

Cancer Commun (Lond)

KRAS-G12D mutation drives immune suppression and the primary resistance of anti-PD-1/PD-L1 immunotherapy in non-small cell lung cancer.

Authors - Chengming Liu
mouseIF

CNS Neurosci Ther

Melatonin Alleviates Behavioral and Neurodevelopmental Abnormalities in Offspring Caused by Prenatal Stress

Authors - Dong Wu
humanIHC

Am J Cancer Res

Identification of potential immune-related circRNA-miRNA-mRNA regulatory network in cutaneous squamous cell carcinoma

Authors - Yuanfeng Wei

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Federica (Verified Customer) (11-07-2023)

I used Alkaline Phospatase Dako kit and Antigen Retrival PH10

  • Applications: Immunohistochemistry
  • Primary Antibody Dilution: 1:200
  • Cell Tissue Type: Healthy Lymphonode
CXCL10/IP-10 Antibody Immunohistochemistry validation (1:200 dilution) in Healthy Lymphonode (Cat no:10937-1-AP)
{{ptg:RelatedPrimaryAntibodies}}