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Anticorps Polyclonal de lapin anti-Connexin-26

Connexin-26 Polyclonal Antibody for WB,ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB,ELISA

Conjugaison

Non conjugué

N° de cat : 51037-2-AP

Synonymes

Connexin 26, Connexin-26, CX26, DFNA3, DFNA3A, DFNB1, DFNB1A, Gap junction beta 2 protein, GJB2, HID, KID, NSRD1, PPK

Galerie de données de validation

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  • Western Blot (WB) analysis of human brain tissue using Connexin-26 Polyclonal antibody (51037-2-AP)

    WB analysis of human brain using 51037-2-AP

    human brain tissue were subjected to SDS PAGE followed by western blot with 51037-2-AP (Connexin-26 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Applications testées

Résultats positifs en WBtissu cérébral humain

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

51037-2-AP cible Connexin-26 dans les applications de WB,ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Peptide
Nom complet gap junction protein, beta 2, 26kDa
Masse moléculaire calculée 26 kDa
Poids moléculaire observé 26 kDa
Numéro d’acquisition GenBankBC017048
Symbole du gène GJB2
Identification du gène (NCBI) 2706
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Connexin-26 (GJB2) is a beta class gap junction protein. Mutations in the gene for connexin-26 are responsible for as much as 50% of pre-lingual, recessive deafness.

Protocole

Product Specific Protocols
WB protocol for Connexin-26 antibody 51037-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols