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Anticorps Monoclonal anti-Fibrinogen Beta Chain

Fibrinogen Beta Chain Monoclonal Antibody for WB,ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB,ELISA

Conjugaison

Non conjugué

CloneNo.

1F8E4

N° de cat : 66186-1-Ig

Synonymes

FGB, fibrinogen beta chain

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of human heart tissue using Fibrinogen Beta Chain Monoclonal antibody (66186-1-Ig)

    WB analysis of human heart using 66186-1-Ig

    human heart tissue were subjected to SDS PAGE followed by western blot with 66186-1-Ig (Fibrinogen beta chain antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of fetal human brain tissue using Fibrinogen Beta Chain Monoclonal antibody (66186-1-Ig)

    WB analysis of fetal human brain using 66186-1-Ig

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66186-1-Ig (Fibrinogen beta chain antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Applications testées

Résultats positifs en WBtissu cardiaque humain, tissu cérébral humain fœtal

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

WBSee 1 publications below

Informations sur le produit

66186-1-Ig cible Fibrinogen Beta Chain dans les applications de WB,ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Réactivité citéeHumain
Hôte / Isotype Mouse / IgG2b
Clonalité Monoclonal
Type Anticorps
Immunogène Fibrinogen Beta Chain Protéine recombinante Ag10205
Nom complet fibrinogen beta chain
Masse moléculaire calculée 491 aa, 56 kDa
Poids moléculaire observé 50 kDa
Numéro d’acquisition GenBankBC107766
Symbole du gène FGB
Identification du gène (NCBI) 2244
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGB is the beta chain of fibrinogen. During conversion of fibrinogen to fibrin, fibrinopeptide B is cleaved from FGB by thrombin. Mutations in the gene of FGB lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Protocole

Product Specific Protocols
WB protocol for Fibrinogen Beta Chain antibody 66186-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Ann Transl Med

LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.

Authors - Yue Guan
View Article