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Anticorps Polyclonal de lapin anti-FOLR1

FOLR1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB

Conjugaison

Non conjugué

N° de cat : 29472-1-AP

Synonymes

Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1 (adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha, KB cells FBP, MOv18

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using FOLR1 Polyclonal antibody (29472-1-AP)

    WB analysis using 29472-1-AP

    HeLa cells were subjected to SDS PAGE followed by western blot with 29472-1-AP (FOLR1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

Applications testées

Résultats positifs en WBcellules HeLa, tissu rénal de rat, tissu rénal de souris

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

29472-1-AP cible FOLR1 dans les applications de WB et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Peptide
Nom complet folate receptor 1 (adult)
Masse moléculaire calculée 257 aa, 30 kDa
Poids moléculaire observé36-38 kDa
Numéro d’acquisition GenBankBC002947
Symbole du gène FOLR1
Identification du gène (NCBI) 2348
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Folate receptor 1 (FOLR1), also known as folate receptor alpha or adult folate-binding protein (FBP), is a 38-kDa glycoprotein belonging to the folate receptor family (PMID:15094207; 23528302). The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung, kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer, non-small cell lung cancer, breast cancer, kidney cancer and high-grade osteosarcoma (PMID: 23528302; 23357463).

Protocole

Product Specific Protocols
WB protocol for FOLR1 antibody 29472-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.

FH

Hua (Verified Customer) (02-14-2023)

Great antibody. Very strong signal.

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:8000
  • Cell Tissue Type: Hela, mouse liver, mouse kidney, mouse brain
FOLR1 Antibody Western Blot validation (1:8000 dilution) in Hela, mouse liver, mouse kidney, mouse brain (Cat no:29472-1-AP)