Anticorps Monoclonal anti-FceR1a

FceR1a Monoclonal Antibody for FC

Hôte / Isotype

Armenian Hamster / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

MAR-1

N° de cat : CL488-65091

Synonymes

MAR-1, High affinity immunoglobulin epsilon receptor subunit alpha, Fcr 5, FcERI, FceR1

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Galerie de données de validation

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  FC experiment of MC/9 using CL488-65091

  1X10^6 MC/9 cells were surface stained with 5 ul CoraLite® Plus 488 Anti-Mouse FceR1 (CL488-65091, Clone:MAR-1) (green) or CoraLite® Plus 488 Armenian Hamster IgG isotype control (black). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules MC/9,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-65091 cible FceR1a dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Armenian Hamster / IgG
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: s/o
• Nom complet: Fc receptor, IgE, high affinity I, alpha polypeptide
• Numéro d’acquisition GenBank: BC125455
• Symbole du gène: FceR1a
• Identification du gène (NCBI): 14125
• Conjugaison: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).

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