Anticorps Polyclonal de lapin anti-Hemopexin

Hemopexin Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris et plus (1)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications

4

N° de cat : 15736-1-AP

Synonymes

Beta 1B glycoprotein, hemopexin, HPX

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Galerie de données de validation

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  WB analysis of human plasma using 15736-1-AP

  human blood were subjected to SDS PAGE followed by western blot with 15736-1-AP (Hemopexin antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse serum using 15736-1-AP

  mouse serum were subjected to SDS PAGE followed by western blot with 15736-1-AP (Hemopexin antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu sanguin humain, plasma humain, sérum de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below
• IHC: See 1 publications below
• IF: See 1 publications below

Informations sur le produit

15736-1-AP cible Hemopexin dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Hemopexin Protéine recombinante Ag8533
• Nom complet: hemopexin
• Masse moléculaire calculée: 254 aa, 29 kDa
• Poids moléculaire observé: 65-75 kDa
• Numéro d’acquisition GenBank: BC005395
• Symbole du gène: HPX
• Identification du gène (NCBI): 3263
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Hemopexin (HPX) is the plasma protein responsible for scavenging heme, thus preventing heme-mediated oxidative stress and heme-bound iron loss. In addition, hemopexin blocks heme activation of immune receptors and vascular inflammatory processes. It is mainly expressed in liver, the synthesis of which is induced after inflammation. Alterations of plasma hemopexin level have been linked to disorders like atherosclerosis and inflammatory diseases.

Publications

Species	Application	Title
human	WB	Br J Cancer; Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.; Authors - Yanxia Jin
rat	IHC	J Cell Biochem; Differential protein expression profiling by iTRAQ-2D-LC-MS/MS of rats treated with oxaliplatin.; Authors - Xianjun Sun
human	WB	Placenta; SWATH proteomics analysis of placental tissue with intrahepatic cholestasis of pregnancy; Authors - Yuxuan Jiang
mouse	IF	Elife; Myoglobin-derived iron causes wound enlargement and impaired regeneration in pressure injuries of muscle; Authors - Nurul Jannah Mohamed Nasir