Anticorps Recombinant de lapin anti-IFN-beta

IFN-beta Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC (Intra)

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

240230B6

N° de cat : CL594-98082

Synonymes

Ifnb1, 240230B6, Ifb, IFN beta, IFNB

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Galerie de données de validation

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  FC experiment of mouse splenocytes using CL594-98082

  1x10^6 mouse splenocytes were intracellularly stained with CoraLite® Plus 488 Anti-Mouse CD19, and 0.25 ug CoraLite®594 Anti-Mouse IFN-beta Rabbit RecAb (CL594-98082, Clone: 240230B6) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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  FC experiment of mouse splenocytes using CL594-98082

  1x10^6 mouse splenocytes were intracellularly stained with 0.25 ug CoraLite®594 Anti-Mouse IFN-beta Rabbit RecAb (CL594-98082, Clone: 240230B6) (red) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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Applications testées

• Résultats positifs en FC (Intra): splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-98082 cible IFN-beta dans les applications de FC (Intra) et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IFN-beta Protéine recombinante Eg0660
• Nom complet: interferon beta 1, fibroblast
• Masse moléculaire calculée: 22KD
• Numéro d’acquisition GenBank: NM_010510.1
• Symbole du gène: Ifnb1
• Identification du gène (NCBI): 15977
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Interferon-beta (IFN-β) is a type I interferon, which is a group of signaling proteins made and released by host cells in response to the presence of several viruses, including double-stranded RNA produced by many viruses. IFN-β is a single protein species and is molecularly related to IFN-α subtypes, although it is antigenically distinct from them. It is mainly produced by fibroblasts and plays a crucial role in the innate immune response against viruses. IFN-β can inhibit viral replication by interfering with the virus's RNA or DNA, thus suppressing viral growth. It also enhances the cytotoxic activity of natural killer (NK) cells and promotes the expression of major histocompatibility complex (MHC) class I molecules.

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