Anticorps Recombinant de lapin anti-IL-28A

IL-28A Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242247E2

N° de cat : 98388-1-RR

Synonymes

Ifnl2, IFN-lambda-2, Il28a, Interferon lambda-2, Interleukin-28A

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98388-1-RR

  1x10^6 HEK-293T cells(left) and Il28a-transfected HEK-293T cells(right) were stained with 0.25 ug Anti-Mouse IL-28A Rabbit RecAb (98388-1-RR, Clone:242247E2) and APC-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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  FC experiment of Transfected HEK-293T using 98388-1-RR

  1x10^6 HEK-293T cells(left) and Il28a-transfected HEK-293T cells(right) were stained with 0.25 ug Anti-Mouse IL-28A Rabbit RecAb (98388-1-RR, Clone:242247E2)(red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and APC-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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  Affinity and Kinetic Characterization of 98388-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98388-1-RR against Mouse IL-28A were performed. The affinity constant is 0.137 nM.

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Applications testées

• Résultats positifs en cytométrie: Transfected HEK-293T cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98388-1-RR cible IL-28A dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: IL-28A Protéine recombinante Eg3169
• Nom complet: interleukin 28A
• Masse moléculaire calculée: 22 kDa
• Numéro d’acquisition GenBank: NM_001024673.2
• Symbole du gène: Il28a
• Identification du gène (NCBI): 330496
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

IL28A, also named as IFNL2 and ZCYT020, is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. IL28A is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. It plays a significant role in the antiviral immune defense in the intestinal epithelium.

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