Anticorps Monoclonal anti-IL-4

IL-4 Monoclonal Antibody for FC (Intra)

Hôte / Isotype

Rat / IgG1, kappa

Réactivité testée

souris

Applications

FC (Intra)

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

11B11

N° de cat : CL488-65074

Synonymes

Il 4, Il4, IL-4, interleukin 4



Applications testées

Résultats positifs en cytométriePMA and ionomycin stimulated mouse Th2-polarized splenocytes

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-65074 cible IL-4 dans les applications de FC (Intra) et montre une réactivité avec des échantillons souris

Réactivité souris
Hôte / Isotype Rat / IgG1, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Partially purified native mouse IL-4
Nom complet interleukin 4
Numéro d’acquisition GenBankBC027514
Symbole du gène Il4
Identification du gène (NCBI) 16189
Conjugaison CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS avec azoture de sodium à 0,1 % et BSA à 0,5 %, pH 7,3.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Interleukin-4 (IL-4), a member of the α-helical cytokine family, is produced by activated CD4+ T cells, basophils, and mast cells. It promotes the proliferation and differentiation of antigen presenting cells. IL-4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL-4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival. (PMID: 24489573;3049907;21663408)

Protocole

Product Specific Protocols
FC protocol for CL Plus 488 IL-4 antibody CL488-65074Download protocol
Standard Protocols
Click here to view our Standard Protocols