Anticorps Monoclonal anti-IL-4
IL-4 Monoclonal Antibody for FC (Intra)
Hôte / Isotype
Rat / IgG1
Réactivité testée
souris
Applications
FC (Intra)
Conjugaison
CoraLite® Plus 647 Fluorescent Dye
CloneNo.
11B11
N° de cat : CL647-65074
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en cytométrie | PMA and ionomycin stimulated mouse Th2-polarized splenocytes |
Dilution recommandée
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Informations sur le produit
CL647-65074 cible IL-4 dans les applications de FC (Intra) et montre une réactivité avec des échantillons souris
Réactivité | souris |
Hôte / Isotype | Rat / IgG1 |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | Partially purified native mouse IL-4 |
Nom complet | interleukin 4 |
Numéro d’acquisition GenBank | BC027514 |
Symbole du gène | Il4 |
Identification du gène (NCBI) | 16189 |
Conjugaison | CoraLite® Plus 647 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 654 nm / 674 nm |
Forme | Liquide |
Méthode de purification | Purification par affinité |
Tampon de stockage | PBS avec azoture de sodium à 0,1 % et BSA à 0,5 %, pH 7,3. |
Conditions de stockage | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Informations générales
Interleukin-4 (IL-4), a member of the α-helical cytokine family, is produced by activated CD4+ T cells, basophils, and mast cells. It promotes the proliferation and differentiation of antigen presenting cells. IL-4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL-4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival. (PMID: 24489573;3049907;21663408)
Protocole
Product Specific Protocols | |
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FC protocol for CL Plus 647 IL-4 antibody CL647-65074 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |