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Anticorps Polyclonal de lapin anti-IL-16

IL-16 Polyclonal Antibody for IHC,ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC,ELISA

Conjugaison

Non conjugué

N° de cat : 13352-1-AP

Synonymes

HsT19289, IL 16, IL16, IL-16, interleukin-16, LCF, prIL 16, Pro interleukin 16

Galerie de données de validation

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  • Immunohistochemistry (IHC) staining of human prostate cancer tissue using IL-16 Polyclonal antibody (13352-1-AP)

    IHC staining of human prostate cancer using 13352-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 13352-1-AP (IL-16 antibody) at dilution of 1:100 (under 10x lens).

Applications testées

Dilution recommandée

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

13352-1-AP cible IL-16 dans les applications de IHC,ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène IL-16 Protéine recombinante Ag4044
Nom complet interleukin 16 (lymphocyte chemoattractant factor)
Masse moléculaire calculée 130 aa, 15 kDa
Numéro d’acquisition GenBankBC040272
Symbole du gène IL16
Identification du gène (NCBI) 3603
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. It is mainly produced by T lymphocytes but also by other immune cells, neuronal cells, fibroblasts and epithelial cells. The signaling process of this cytokine is mediated by CD4. IL-16 induces chemotaxis of CD4+ cells such as lymphocytes, eosinophils, and dendritic cells by ligating CD4 directly at a site distinct from other ligands. Among its multiple functions, IL-16 is a T cell chemoattractant involved in T helper cell inflammatory responses and the regulation of both T cell growth, and responsiveness to regulatory cytokines. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control.