Anticorps Polyclonal de lapin anti-Inhibin Beta A

• Phare
• Validé par KD/KO

Inhibin Beta A Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain et plus (1)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(18)

N° de cat : 10651-1-AP

Synonymes

INHBA, Inhibinβ-A, inhibin, beta A, Inhibin β-A, EDF

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Galerie de données de validation

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Applications publiées

• KD/KO: See 1 publications below
• WB: See 5 publications below
• IHC: See 12 publications below
• IF: See 3 publications below

Informations sur le produit

10651-1-AP cible Inhibin Beta A dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Inhibin Beta A Protéine recombinante Ag1001
• Nom complet: inhibin, beta A
• Masse moléculaire calculée: 47 kDa
• Poids moléculaire observé: 42 kDa
• Numéro d’acquisition GenBank: BC007858
• Symbole du gène: Inhibin beta A
• Identification du gène (NCBI): 3624
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Inhibin is a 32-kD dimeric glycoprotein consisting of an alpha subunit and one of two beta subunits (beta A or beta B) leading to inhibin A or B, respectively, which was isolated and cloned on the basis of its ability to inhibit FSH release from the pituitary. Inhibin beta A forms a disulfide-linked homo-dimer known as activin A, which has been implicated in multiple biologic processes, including neoplastic progression. The inhibin beta A can also bind the beta B and A isoforms to form activin AB and inhibin, respectively.

Publications

Species	Application	Title
human	IF	Nat Commun; Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.; Authors - Yi-Ing Chen
		Development; Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination.; Authors - Dipankar J Dutta
	IHC	Cells; Single-Cell RNA-Seq Reveals Transcriptomic Heterogeneity and Post-Traumatic Osteoarthritis-Associated Early Molecular Changes in Mouse Articular Chondrocytes.; Authors - Aimy Sebastian
mouse	WB	PLoS One; Action mechanism of inhibin α-subunit on the development of Sertoli cells and first wave of spermatogenesis in mice.; Authors - Cai Kailai K
human	IHC,IF	Transl Oncol; Multiregion single cell analysis reveals a novel subtype of cancer-associated fibroblasts located in the hypoxic tumor microenvironment in colorectal cancer; Authors - Nanxin Zheng
		Hepatol Commun; Activin A is a prominent autocrine regulator of hepatocyte growth arrest.; Authors - Srividyameena Haridoss

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