Anticorps Polyclonal de lapin anti-LSAMP

LSAMP Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 13600-1-AP

Synonymes

IgLON family member 3, IGLON3, LAMP, LSAMP

---

Galerie de données de validation

• 

  WB analysis of human brain using 13600-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 13600-1-AP (LSAMP antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse brain using 13600-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 13600-1-AP (LSAMP antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

---

Applications testées

• Résultats positifs en WB: tissu cérébral humain, tissu cérébral de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

13600-1-AP cible LSAMP dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LSAMP Protéine recombinante Ag4542
• Nom complet: limbic system-associated membrane protein
• Masse moléculaire calculée: 338 aa, 37 kDa
• Poids moléculaire observé: 64-68 kDa
• Numéro d’acquisition GenBank: BC033803
• Symbole du gène: LSAMP
• Identification du gène (NCBI): 4045
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

LSAMP, also known as LAMP, is a 64-68 kDa heavily glycosylated neural cell adhesion molecule expressed on the neuronal dendrites and somata (PMID: 1688937; 8666243). LSAMP is a member of the IgLON family. The amino acid sequence of LSAMP is highly conserved among species. Human LSAMP shares 99% amino acid sequence identity with rodent LSAMP. The impact of LSAMP protein on neurite outgrowth and neuronal connectivity has been established in a wide spectrum of psychiatric disorders in humans (PMID: 26136648). In mice, lack of LSAMP protein seemingly leads to a deterioration in the ability to adapt to novel stressful environments and stimuli (PMID: 22155487).

{{ptg:RelatedPrimaryAntibodies}}