Anticorps Monoclonal anti-M-CSF

M-CSF Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

3G12E6

N° de cat : CL647-65283

Synonymes

CSF 1, CSF1, Lanimostim, M CSF, MCSF



Applications testées

Résultats positifs en cytométrieLPS and Brefeldin A treated human PBMCs,

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-65283 cible M-CSF dans les applications de FC et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène M-CSF Protéine recombinante HZ-1192
Nom complet colony stimulating factor 1 (macrophage)
Masse moléculaire calculée 60 kDa
Numéro d’acquisition GenBankBC021117
Symbole du gène CSF1
Identification du gène (NCBI) 1435
Conjugaison CoraLite® Plus 647 Fluorescent Dye
Excitation/Emission maxima wavelengths654 nm / 674 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide and 0.5% BSA.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

M-CSF plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes. M-CSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. On the cellular level, M-CSF promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration and plays a role in lipoprotein clearance (PMID: 29734839; 29679908; 28202039)

Protocole

Product Specific Protocols
FC protocol for CL Plus 647 M-CSF antibody CL647-65283Download protocol
Standard Protocols
Click here to view our Standard Protocols