Anticorps Polyclonal de lapin anti-Malectin

• Phare
• Validé par KD/KO

Malectin Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF, ELISA

Conjugaison

Non conjugué

Publications(8)

N° de cat : 26655-1-AP

Synonymes

MLEC, KIAA0152

---

Galerie de données de validation

• 

  WB analysis using 26655-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 26655-1-AP (Malectin antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human placenta using 26655-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 26655-1-AP (Malectin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human placenta using 26655-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 26655-1-AP (Malectin antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

---

Applications testées

• Résultats positifs en WB: tissu de côlon de souris, tissu de côlon de rat, tissu placentaire humain

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 7 publications below
• IF: See 2 publications below

Informations sur le produit

26655-1-AP cible Malectin dans les applications de WB, IF, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Malectin Protéine recombinante Ag24379
• Nom complet: malectin
• Masse moléculaire calculée: 292 aa, 32 kDa
• Poids moléculaire observé: 32 kDa
• Numéro d’acquisition GenBank: BC000371
• Symbole du gène: Malectin
• Identification du gène (NCBI): 9761
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Malectin is a conserved, endoplasmic reticulum (ER)-resident lectin that recognizes high mannose oligosaccharides displaying terminal glucose residues. Like other intracellular lectins involved in glycoprotein quality control, malectin is highly conserved in animals (PMID: 21298103).

Publications

Species	Application	Title
rat	WB	J Cell Biol; Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins; Authors - Amber M Cheatham
human	WB	Exp Cell Res; Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.; Authors - Ning Jiang ; KD Validated
		Mol Biol Cell; The prolyl isomerase FKBP11 is a secretory translocon accessory factor; Authors - Amanda DiGuilio
human	WB	Biochemistry; Integrated Structural Analysis of N-Glycans and Free Oligosaccharides Allows for a Quantitative Evaluation of ER Stress.; Authors - Naoki Fujitani
mouse	WB,IF	Nat Commun; The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes; Authors - Shuangcheng Alivia Wu
human	WB,IF	Int Immunopharmacol; Identification of TAP1 as a T-cell related therapeutic target in gastric cancer by mediating oxalipliatin-related synergistic enhancement of immunotherapy; Authors - Yupeng Zhao

{{ptg:RelatedPrimaryAntibodies}}