Anticorps Polyclonal de lapin anti-RFX6

RFX6 Polyclonal Antibody for WB,ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

Publications

1

N° de cat : 22551-1-AP

Synonymes

DNA binding protein RFX6, Regulatory factor X 6, regulatory factor X, 6, RFX6, RFXDC1

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Galerie de données de validation

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  WB analysis of Caco-2 using 22551-1-AP

  Caco-2 cells were subjected to SDS PAGE followed by western blot with 22551-1-AP (RFX6 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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  WB analysis of Caco-2 using 22551-1-AP

  Caco-2 cells were subjected to SDS PAGE followed by western blot with 22551-1-AP (RFX6 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules Caco-2

Dilution recommandée

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 1 publications below
• IHC: See 1 publications below

Informations sur le produit

22551-1-AP cible RFX6 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RFX6 Protéine recombinante Ag18235
• Nom complet: regulatory factor X, 6
• Masse moléculaire calculée: 928 aa, 102 kDa
• Poids moléculaire observé: 102 kDa
• Numéro d’acquisition GenBank: BC039248
• Symbole du gène: RFX6
• Identification du gène (NCBI): 222546
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The RFX proteins represent an essential class II transcription factor family that share several conserved regions, including a centrally located DNA-binding domain (DBD) and a C-terminal D region that facilitates dimerization. RFX6, also known as RFXDC1, is a 928 amino acid nuclear protein that, via interactions with other RFX proteins, can bind DNA and is thought to activate the transcription of target genes. RFX6 is specifically expressed in pancreas, small intestine and colon. Mutations in the gene encoding RFX6 is the cause of the Mitchell-Riley syndrome (MIRIS), which is characterized by neonatal diabetes, duodenal and jejunal atresia, a hypoplastic or annular pancreas and absent gallbladder.

Publications

Species	Application	Title
human	WB,IHC	Clin Transl Med; RFX6 facilitates aerobic glycolysis-mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1; Authors - Zhiyu Qiu ; KD Validated