Anticorps Polyclonal de lapin anti-RPGRIP1L

RPGRIP1L Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris et plus (1)

Applications

WB, IF, ELISA

Conjugaison

Non conjugué

Publications(4)

N° de cat : 29778-1-AP

Synonymes

CORS3, DKFZp686C0668, FTM, JBTS7, KIAA1005, MKS5, Protein fantom, RPGRIP1 like, RPGRIP1 like protein, RPGRIP1L

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Galerie de données de validation

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  WB analysis using 29778-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 29778-1-AP (RPGRIP1L antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

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  WB analysis using 29778-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 29778-1-AP (RPGRIP1L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse testis using 29778-1-AP

  Mouse testis tissue were subjected to SDS PAGE followed by western blot with 29778-1-AP (RPGRIP1L antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HeLa, cellules HEK-293, cellules Jurkat, tissu testiculaire de rat, tissu testiculaire de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below
• IF: See 2 publications below

Informations sur le produit

29778-1-AP cible RPGRIP1L dans les applications de WB, IF, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain, poisson-zèbre, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RPGRIP1L Protéine recombinante Ag31168
• Nom complet: RPGRIP1-like
• Masse moléculaire calculée: 151 kDa
• Poids moléculaire observé: 151 kDa
• Numéro d’acquisition GenBank: NM_015272
• Symbole du gène: RPGRIP1L
• Identification du gène (NCBI): 23322
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

RPGRIP1L, also named as FTM, KIAA1005, belongs to the RPGRIP1 family. It negatively regulates signaling through the G-protein coupled thromboxane A2 receptor. RPGRIP1L may be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis.(PMID:17558409) Defects in RPGRIP1L are the cause of Joubert syndrome type 7 (JBTS7). Defects in RPGRIP1L are the cause of Meckel syndrome type 5 (MKS5).

Publications

Species	Application	Title
human	IF	Elife; Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis; Authors - Emma A Hall
human,zebrafish	WB	Dis Model Mech; Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants; Authors - Jun Wang
	IF	bioRxiv; Two functional forms of the Meckel-Gruber syndrome protein TMEM67 generated by proteolytic cleavage by ADAMTS9 mediate Wnt signaling and ciliogenesis; Authors - Manu Ahmed
mouse	WB	Cell Mol Neurobiol; Downregulation of Hmox1 and Rpgrip1l Expression Linked to Risk-Taking Behavior, Reduced Depressive Symptoms, and Diminished Novelty Socialization in SUMO1 Knockout Mice; Authors - Qiwei Dai

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