Anticorps Polyclonal de lapin anti-SLC37A2

SLC37A2 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

Publications(2)

N° de cat : 20469-1-AP

Synonymes

pp11662, SLC37A2, SPX2, Sugar phosphate exchanger 2

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Galerie de données de validation

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  WB analysis of mouse thymus using 20469-1-AP

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 20469-1-AP (SLC37A2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis using 20469-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 20469-1-AP (SLC37A2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse spleen using 20469-1-AP

  mouse spleen tissue were subjected to SDS PAGE followed by western blot with 20469-1-AP (SLC37A2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of RAW 264.7 using 20469-1-AP

  RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 20469-1-AP (SLC37A2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu de thymus de souris, cellules HeLa, cellules RAW 264.7, tissu de thymus de rat, tissu splénique de souris

Dilution recommandée

• Western Blot (WB): WB : 1:300-1:600

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below
• IHC: See 1 publications below

Informations sur le produit

20469-1-AP cible SLC37A2 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC37A2 Protéine recombinante Ag14306
• Nom complet: solute carrier family 37 (glycerol-3-phosphate transporter), member 2
• Masse moléculaire calculée: 505 aa, 55 kDa
• Poids moléculaire observé: 50-75 kDa
• Numéro d’acquisition GenBank: BC051314
• Symbole du gène: SLC37A2
• Identification du gène (NCBI): 219855
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The solute carrier family 37 (SLC37) consists of four sugar-phosphate exchangers, A1, A2, A3, and A4, which are anchored in the endoplasmic reticulum (ER) membrane (PMID:23506893). Solute Carrier Family 37 Member 2 (SLC37A2), also knows as SPX2, was firstly identified in a work, conducted on mice and aimed to detect cAMP inducible genes playing a role in promoting cholesterol efflux from the macrophage cell line RAW264 via apoE and apoA1 (PMID:11004510). Interestingly, of the four SLC37A members, SLC37A2 displays the highest level of transcript abundance in neutrophils and macrophages ,indicating that SLC37A2 may play an essential role in regulating innate immune function (PMID:32428862).

Publications

Species	Application	Title
human	WB,IHC	Cell Biol Toxicol; hucMSC-Ex alleviates inflammatory bowel disease in mice by enhancing M2-type macrophage polarization via the METTL3-Slc37a2-YTHDF1 axis; Authors - Xinwei Xu
mouse	WB	J Asian Nat Prod Res; Chlorogenic acid targets SLC37A2 to inhibit macrophage activation via ER-dependent NF-κB and NLRP3 signaling pathways against sepsis-induced acute lung injury; Authors - Yang Chen

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