Anticorps Polyclonal de lapin anti-STRA6

STRA6 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris et plus (1)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(12)

Avis (1)

N° de cat : 22001-1-AP

Synonymes

MCOPS9, PP14296, STRA6, UNQ3126/PRO10282/PRO19578

---

Galerie de données de validation

• 

  WB analysis using 22001-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 22001-1-AP (STRA6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 22001-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 22001-1-AP (STRA6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

---

Applications testées

• Résultats positifs en WB: tissu rénal de souris, tissu rénal de rat

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 9 publications below
• IHC: See 3 publications below
• IF: See 3 publications below

Informations sur le produit

22001-1-AP cible STRA6 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: STRA6 Protéine recombinante Ag17591
• Nom complet: stimulated by retinoic acid gene 6 homolog (mouse)
• Masse moléculaire calculée: 667 aa, 74 kDa
• Poids moléculaire observé: 73-78 kDa
• Numéro d’acquisition GenBank: BC025256
• Symbole du gène: STRA6
• Identification du gène (NCBI): 64220
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

STRA6, also known as MCOPS9 and PP14296. Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin. (PMID:9452451; 18316031; 22665496; 21368206; 22665496).

Publications

Species	Application	Title
mouse	WB	J Cachexia Sarcopenia Muscle; RBP4 promotes denervation-induced muscle atrophy through STRA6-dependent pathway; Authors - Kang-Zhen Zhang
mouse	IF,WB	Int J Mol Sci; Retinoid Regulation of Ocular Surface Innate Inflammation.; Authors - Jehan Alam
human	IF	Sci Rep; TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.; Authors - S Prpar Mihevc
human	WB	Cancers (Basel); ANLN Promotes the Proliferation and Migration of Gallbladder Cancer Cells via STRA6-Mediated Activation of PI3K/AKT Signaling; Authors - Xiang Zhu
human	IF	Endocrinology; De novo-synthesized retinoic acid in ovarian antral follicles enhances FSH-mediated ovarian follicular cell differentiation and female fertility.; Authors - Tomoko Kawai
mouse	IHC	Lab Invest; Nuclear receptor binding factor 2 (NRBF2) is required for learning and memory.; Authors - Xiaosen Ouyang

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.

---

FH

Christian (Verified Customer) (02-19-2020)

The antibody works quite well, not many unspecific bands.

• Applications: Western Blot,
• Cell Tissue Type: HUVEC

{{ptg:RelatedPrimaryAntibodies}}