Anticorps Recombinant de lapin anti-TLR3/CD283

TLR3/CD283 Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC (Intra)

Conjugaison

Biotin

CloneNo.

230445F1

N° de cat : Biotin-FcA98016

Synonymes

TLR3, 230445F1, CD283, toll like receptor 3, Toll-like receptor 3

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Galerie de données de validation

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  FC experiment of Human immature monocyte-derived dendritic cells using Biotin-FcA98016

  1x10^6 Human immature monocyte-derived dendritic cells were intracellularly stained with 0.25 ug Biotin Anti-Human TLR3/CD283 Rabbit RecAb (Biotin-FcA98016, Clone: 230445F1) or FcZero-rAb™ Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9), and PE-conjugated streptavidin. Cells were co-stained with FcZero-rAb™ APC Anti-Human CD11c (3.9). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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Applications testées

• Résultats positifs en FC (Intra): Human immature monocyte-derived dendritic cells

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-FcA98016 cible TLR3/CD283 dans les applications de FC (Intra) et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TLR3/CD283 Protéine recombinante Ag34044
• Nom complet: toll-like receptor 3
• Masse moléculaire calculée: 904 aa, 104 kDa
• Numéro d’acquisition GenBank: BC094737
• Symbole du gène: TLR3
• Identification du gène (NCBI): 7098
• Conjugaison: Biotin
• Excitation/Emission maxima wavelengths: -
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

TLR3 belongs to the Toll-like receptor family which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA. Upon recognition of dsRNA, TLR3 transmits signals via the adaptor protein TICAM-1/TRIF, leading to the induction of type I IFN, cytokine/chemokine production, and dendritic cell (DC) maturation (PMID: 18262679).

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