Anticorps Recombinant de lapin anti-TSLP

TSLP Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

241821B2

N° de cat : 98247-1-RR

Synonymes

Thymic stromal lymphopoietin, 241821B2

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Galerie de données de validation

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  FC experiment of HUVEC using 98247-1-RR

  1x10^6 untreated or IL-4, TNF-α and BFA-treated HUVEC cells were intracellularly stained with 0.25 ug Anti-Human TSLP Rabbit RecAb (98247-1-RR, Clone: 241821B2) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

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  Affinity and Kinetic Characterization of 98247-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98247-1-RR against Human TSLP were performed. The affinity constant is 2.85 nM.

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Applications testées

• Résultats positifs en FC (Intra): IL-4, TNF-α and BFA treated HUVEC cells

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98247-1-RR cible TSLP dans les applications de FC (Intra) et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: thymic stromal lymphopoietin
• Masse moléculaire calculée: 18 kDa
• Numéro d’acquisition GenBank: NM_033035.5
• Symbole du gène: TSLP
• Identification du gène (NCBI): 85480
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain, it mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. Another isoform of this protein may act as an antimicrobial peptide in the oral cavity and on the skin (PMID: 24850429).

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