- Phare
- Validé par KD/KO
Anticorps Polyclonal de lapin anti-VLDLR
VLDLR Polyclonal Antibody for WB, IF/ICC, ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain et plus (4)
Applications
WB, IF/ICC, ELISA
Conjugaison
Non conjugué
N° de cat : 19493-1-AP
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en WB | cellules MCF-7, |
| Résultats positifs en IF/ICC | cellules HeLa, |
Dilution recommandée
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| KD/KO | See 1 publications below |
| WB | See 10 publications below |
| IF | See 1 publications below |
Informations sur le produit
19493-1-AP cible VLDLR dans les applications de WB, IF/ICC, ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Réactivité citée | rat, Humain, poisson-zèbre, poulet, souris |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | Peptide |
| Nom complet | very low density lipoprotein receptor |
| Masse moléculaire calculée | 96 kDa |
| Poids moléculaire observé | 96 kDa |
| Numéro d’acquisition GenBank | NM_003383 |
| Symbole du gène | VLDLR |
| Identification du gène (NCBI) | 7436 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS with 0.02% sodium azide and 50% glycerol |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
VLDLR binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. VLDLR binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (cytoplasmic domain of low-density lipoprotein receptor). For glycosylated, the MW of VLDLR migrates to ~160kd.
Protocole
| Product Specific Protocols | |
|---|---|
| WB protocol for VLDLR antibody 19493-1-AP | Download protocol |
| IF protocol for VLDLR antibody 19493-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Neuron Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning. | ||
Food Funct Monounsaturated fatty acid-enriched olive oil exacerbates chronic alcohol-induced hepatic steatosis and liver injury in C57BL/6J mice | ||
Front Pharmacol Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats. | ||
PLoS One Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency. | ||
Front Nutr Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol | ||
Front Oncol VLDLR disturbs quiescence of breast cancer stem cells in a ligand-independent function
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Avis
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH natalia (Verified Customer) (01-31-2025) |
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